PMID- 1491199
OWN - NLM
STAT- MEDLINE
DCOM- 19930301
LR  - 20110727
IS  - 0369-4739 (Print)
IS  - 0369-4739 (Linking)
VI  - 40
IP  - 12
DP  - 1992 Dec
TI  - [Evaluation of the correlation with preoperative left ventricular end-systolic 
      volume index and postoperative exercise tolerance in the patient with aortic 
      regurgitation].
PG  - 2197-204
AB  - Twenty-three male patients (49 +/- 11 years old) undergoing aortic valve 
      replacement (AVR) for aortic regurgitation received the exercise tolerance test 
      using bicycle ergometer at more than one year after AVR. Preoperative left 
      ventricular end-systolic volume index (LVESVI) significantly correlated with 
      tolerance time, peak VO2, anaerobic threshold (AT) during the exercise, and with 
      serum noradrenaline (NAd) levels at rest. Then patients were divided into two 
      groups: those with preoperative LVESVI < or = 70 ml/M2 (13 patients, group A), 
      and those with LVESVI > 70 ml/M2 (10 patients, group B). All patient in group A 
      achieved more than 75 W of the exercise, however only one in group B achieved 
      this level. The increase of VO2 in group B with an increasing exercise was 
      significantly suppressed compared to group A, and then, the peak VO2 levels in 
      group B were significantly lower than in group A (A: 20.9 +/- 3.7, B: 11.4 +/- 
      3.9 ml/kg/min). In addition group B showed a less increase of AT levels (A: 10.6 
      +/- 2.9, B: 6.8 +/- 2.3 ml/kg/min). In contrast, serum lactate and NAd levels in 
      group B increased significantly at 50 W of the exercise compared to group A (A: 
      12.5 +/- 3.7, 332.3 +/- 104.2; B: 17.5 +/- 5.7 mg/dl, 746.7 +/- 324.3 pg/ml, 
      respectively) though a significant difference of NAd levels before the exercise 
      was observed between the both groups (A: 173.7 +/- 34.2, B: 329.0 +/- 132.1). In 
      conclusion, group A showed a better exercise tolerance physiologically and 
      biochemically compared to group B.(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Minowa, T
AU  - Minowa T
AD  - Second Department of Surgery, Yamagata University School of Medicine, Japan.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Kyobu Geka Gakkai Zasshi
JT  - [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
JID - 19130180R
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Anaerobic Threshold
MH  - Aortic Valve Insufficiency/*physiopathology/surgery
MH  - Exercise Test
MH  - Heart Valve Prosthesis
MH  - Hemodynamics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Physical Endurance/*physiology
MH  - Postoperative Period
MH  - Systole
MH  - Ventricular Function, Left/*physiology
EDAT- 1992/12/01 00:00
MHDA- 1992/12/01 00:01
CRDT- 1992/12/01 00:00
PHST- 1992/12/01 00:00 [pubmed]
PHST- 1992/12/01 00:01 [medline]
PHST- 1992/12/01 00:00 [entrez]
PST - ppublish
SO  - Nihon Kyobu Geka Gakkai Zasshi. 1992 Dec;40(12):2197-204.