PMID- 14965864
OWN - NLM
STAT- MEDLINE
DCOM- 20040805
LR  - 20071115
IS  - 1024-5332 (Print)
IS  - 1024-5332 (Linking)
VI  - 9
IP  - 1
DP  - 2004 Feb
TI  - The use of fluorescence in situ hybridization (FISH) in chronic lymphocytic 
      leukemia (CLL).
PG  - 11-5
AB  - As a result of the low proliferative index, only 50% of chronic lymphocytic 
      leukemia cases are adequate for cytogenetic analysis. Of these, about half have 
      clonal abnormalities. The application of fluorescence in situ hybridization 
      (FISH) to CLL has substantially enhanced our ability to detect chromosomal 
      aberrations; the incidence of a number of recurring abnormalities has been 
      established, providing new insights into the pathogenesis of this disease with a 
      direct impact on the prognosis.
FAU - Gozzetti, Alessandro
AU  - Gozzetti A
AD  - Department of Medicine and Immunological Sciences, University of Siena, Italy. 
      gozzetti@unisi.it
FAU - Crupi, Rosaria
AU  - Crupi R
FAU - Tozzuoli, Daniela
AU  - Tozzuoli D
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Hematology
JT  - Hematology (Amsterdam, Netherlands)
JID - 9708388
SB  - IM
MH  - Chromosome Aberrations
MH  - Humans
MH  - *In Situ Hybridization, Fluorescence
MH  - Leukemia, Lymphocytic, Chronic, B-Cell/*genetics
RF  - 28
EDAT- 2004/02/18 05:00
MHDA- 2004/08/06 05:00
CRDT- 2004/02/18 05:00
PHST- 2004/02/18 05:00 [pubmed]
PHST- 2004/08/06 05:00 [medline]
PHST- 2004/02/18 05:00 [entrez]
AID - 3PMNJ327C9QJF9QN [pii]
AID - 10.1080/10245330310001652446 [doi]
PST - ppublish
SO  - Hematology. 2004 Feb;9(1):11-5. doi: 10.1080/10245330310001652446.