PMID- 14979398
OWN - NLM
STAT- MEDLINE
DCOM- 20041109
LR  - 20220318
IS  - 1076-0296 (Print)
IS  - 1076-0296 (Linking)
VI  - 10
IP  - 1
DP  - 2004 Jan
TI  - Prevention of thromboembolism with low-molecular-weight heparin in orthopedic 
      surgery: a 5-year experience.
PG  - 1-4
AB  - A regimen of prophylaxis of thromboembolism with low molecular weight heparin 
      (LMWH) and unfractionated heparin (UFH) in orthopedic surgery is presented. Over 
      a 5-year period, 11,905 patients have been operated in all fields of orthopedic 
      surgery in a big trauma center. In 498 cases, deep vein thrombosis (DVT) was 
      clinically suspected and phlebography was performed: 122 patients had confirmed 
      DVT (rate 0.98%); 59.8% of the DVT were limited to the calf. Nineteen pulmonary 
      embolisms (rate 0.16%) were diagnosed (3 lethal). Heparin-induced 
      thrombocytopenia type II was diagnosed in 12 of 122 patients. Only one of these 
      had received LMWH. The related rates of DVT were highest for tibial head 
      fractures (12.4%), total knee replacement (6.7%), and multiple trauma (6.4%). The 
      extent of DVT was most severe in multiple trauma. The results proved the regimen 
      to be of good clinical use and showed that more attention has to be paid to 
      fractures, especially of the knee; and to patients with multiple injuries.
FAU - Wenzl, M E
AU  - Wenzl ME
AD  - Department of Orthopedic Surgery, BG Trauma Centre, Hamburg, Germany. 
      michael.wenzl@chirurgie.uni-luebeck.de
FAU - Hasse, W
AU  - Hasse W
FAU - Seide, K
AU  - Seide K
FAU - Wolter, D
AU  - Wolter D
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Clin Appl Thromb Hemost
JT  - Clinical and applied thrombosis/hemostasis : official journal of the 
      International Academy of Clinical and Applied Thrombosis/Hemostasis
JID - 9508125
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 9005-49-6 (Heparin)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Clinical Trials as Topic
MH  - Drug Evaluation
MH  - Female
MH  - Heparin/adverse effects/immunology/therapeutic use
MH  - Heparin, Low-Molecular-Weight/adverse effects/*therapeutic use
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Middle Aged
MH  - Orthopedic Procedures/*adverse effects
MH  - Perioperative Care
MH  - Phlebography
MH  - Postoperative Complications/prevention & control
MH  - Retrospective Studies
MH  - Thromboembolism/diagnosis/*prevention & control
MH  - Thrombosis/chemically induced
EDAT- 2004/02/26 05:00
MHDA- 2004/11/13 09:00
CRDT- 2004/02/26 05:00
PHST- 2004/02/26 05:00 [pubmed]
PHST- 2004/11/13 09:00 [medline]
PHST- 2004/02/26 05:00 [entrez]
AID - 10.1177/107602960401000101 [doi]
PST - ppublish
SO  - Clin Appl Thromb Hemost. 2004 Jan;10(1):1-4. doi: 10.1177/107602960401000101.