PMID- 14983872
OWN - NLM
STAT- MEDLINE
DCOM- 20040915
LR  - 20190922
IS  - 1046-7408 (Print)
IS  - 1046-7408 (Linking)
VI  - 51
IP  - 2
DP  - 2004 Feb
TI  - Correlation between serum estradiol in the follicular phase of the ovarian cycle 
      and decay acceleration factor (DAF) expression on red blood cells and 
      coxsackiervirus B-3 induced hemagglutination in young cycling women.
PG  - 180-7
AB  - Decay accelerating factor (DAF) is a widely distributed glycoprotein which aids 
      in the inactivation of complement. DAF is also a cellular receptor for certain 
      group B coxsackieviruses (CVB) and is responsible for the viral hemagglutinating 
      activity for human red blood cells (RBC). Healthy, young female volunteers 
      donated blood on days 11 and 22 of the ovarian cycle. Samples were categorized 
      into luteal and follicular phases based on serum progesterone level (P4 either < 
      2.0 ng/mL, follicular; P4 > or = 2.0 ng/mL, luteal) and analyzed by flow 
      cytomtery for DAF expression on RBC and CD21 + B lymphocytes. Cycling females 
      showed significant variation in CVB-induced hemagglutination and % RBC or CD19 + 
      cells which were DAF +. There was a strong correlation between serum estradiol 
      levels and % RBC expressing DAF (P < 0.01) in the follicular, but not in the 
      luteal ovarian phase. Infection of white blood cells with green-fluorescent 
      protein CVB (GFP-CVB) showed a correlation between infectivity of CD19+ cells and 
      DAF expression. This indicates that women may show differential susceptibility to 
      CVB infection in the luteal and follicular phases of the ovarian cycle.
FAU - Sartini, Danielle
AU  - Sartini D
AD  - University of Vermont, Burlington, VT 05446, USA.
FAU - Moussawi, Mohamad
AU  - Moussawi M
FAU - Sallam, Reem
AU  - Sallam R
FAU - Bernstein, Ira
AU  - Bernstein I
FAU - Huber, Sally
AU  - Huber S
LA  - eng
GR  - HL 46696/HL/NHLBI NIH HHS/United States
GR  - HL 58329/HL/NHLBI NIH HHS/United States
GR  - HL 63101/HL/NHLBI NIH HHS/United States
GR  - M01-RR109/RR/NCRR NIH HHS/United States
GR  - R21 AI51850/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Denmark
TA  - Am J Reprod Immunol
JT  - American journal of reproductive immunology (New York, N.Y. : 1989)
JID - 8912860
RN  - 0 (Antigens, CD19)
RN  - 0 (CD55 Antigens)
RN  - 0 (Luminescent Proteins)
RN  - 0 (Recombinant Proteins)
RN  - 147336-22-9 (Green Fluorescent Proteins)
RN  - 4G7DS2Q64Y (Progesterone)
RN  - 4TI98Z838E (Estradiol)
SB  - IM
MH  - Antigens, CD19/immunology
MH  - CD55 Antigens/*blood/immunology
MH  - Enterovirus B, Human/genetics/*immunology/pathogenicity
MH  - Enterovirus Infections/blood/immunology
MH  - Erythrocytes/*immunology/virology
MH  - Estradiol/*blood
MH  - Female
MH  - Follicular Phase/blood
MH  - Green Fluorescent Proteins
MH  - Hemagglutination/immunology
MH  - Humans
MH  - Leukocytes/cytology
MH  - Luminescent Proteins
MH  - Luteal Phase/blood
MH  - Menstrual Cycle/*blood/immunology
MH  - Progesterone/blood
MH  - Recombinant Proteins
EDAT- 2004/02/27 05:00
MHDA- 2004/09/16 05:00
CRDT- 2004/02/27 05:00
PHST- 2004/02/27 05:00 [pubmed]
PHST- 2004/09/16 05:00 [medline]
PHST- 2004/02/27 05:00 [entrez]
AID - 10.1046/j.8755-8920.2003.00142.x [doi]
PST - ppublish
SO  - Am J Reprod Immunol. 2004 Feb;51(2):180-7. doi: 10.1046/j.8755-8920.2003.00142.x.