PMID- 14988043
OWN - NLM
STAT- MEDLINE
DCOM- 20040624
LR  - 20071114
IS  - 0006-8993 (Print)
IS  - 0006-8993 (Linking)
VI  - 1002
IP  - 1-2
DP  - 2004 Mar 26
TI  - Photoperiodic regulation of vasopressin receptor binding in female Syrian 
      hamsters.
PG  - 136-41
AB  - During long "summer-like" photoperiods, female Syrian hamsters display a regular 
      4-day estrous cycle. However, during short "winter-like" photoperiods (<12.5 h of 
      light/day) hamsters become anestrus. Short photoperiod exposure eliminates 
      reproductive behavior but social behaviors such as aggression and scent marking 
      continue to be displayed. In long photoperiods, the types and intensity of social 
      behaviors change as a function of the estrous cycle. For example, aggression and 
      scent marking tend to occur at higher levels on diestrus 1 and diestrus 2 than on 
      proestrus or estrus. Aggression and scent marking may be regulated, at least in 
      part, by changes in the density of arginine vasopressin-V(1a) receptors (V(1a)R). 
      In Experiment 1, it was hypothesized that the density of V(1a)R would change 
      across the estrous cycle in several subcortical regions implicated in the 
      regulation of aggression and scent marking. In Experiment 2, it was hypothesized 
      that exposure to short photoperiod would alter the density of V(1a)R in several 
      regions involved in the regulation of social behavior. Interestingly, there were 
      no dramatic changes in V(1a)R binding across the estrous cycle within any of the 
      neuroanatomical areas measured. However, in hamsters housed in short photoperiod, 
      there were lower levels of V(1a)R binding within the medial preoptic nucleus 
      (MPN), medial preoptic area (MPO), lateral hypothalamus (LH), central nucleus of 
      the amygdala (Ce) and bed nucleus of the stria terminalis (BST) than in hamsters 
      housed in long photoperiod. These data suggest that photoperiodic mechanisms can 
      alter the density of V(1a)R in subset of V(1a) binding sites thought to be 
      involved in the regulation of social behaviors in female hamsters.
FAU - Caldwell, Heather K
AU  - Caldwell HK
AD  - Center for Behavioral Neuroscience, Department of Biology, Atlanta, GA 30303, 
      USA.
FAU - Albers, H Elliott
AU  - Albers HE
LA  - eng
GR  - MH62641/MH/NIMH NIH HHS/United States
GR  - NS37232/NS/NINDS NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - Netherlands
TA  - Brain Res
JT  - Brain research
JID - 0045503
RN  - 0 (Receptors, Vasopressin)
SB  - IM
MH  - Animals
MH  - Brain/*metabolism
MH  - Cricetinae
MH  - Estrous Cycle/*metabolism
MH  - Female
MH  - Mesocricetus
MH  - *Photoperiod
MH  - Protein Binding/physiology
MH  - Receptors, Vasopressin/*metabolism
EDAT- 2004/02/28 05:00
MHDA- 2004/06/25 05:00
CRDT- 2004/02/28 05:00
PHST- 2003/12/23 00:00 [accepted]
PHST- 2004/02/28 05:00 [pubmed]
PHST- 2004/06/25 05:00 [medline]
PHST- 2004/02/28 05:00 [entrez]
AID - S0006899304000277 [pii]
AID - 10.1016/j.brainres.2003.12.025 [doi]
PST - ppublish
SO  - Brain Res. 2004 Mar 26;1002(1-2):136-41. doi: 10.1016/j.brainres.2003.12.025.