PMID- 14996276
OWN - NLM
STAT- MEDLINE
DCOM- 20040406
LR  - 20191108
IS  - 1354-523X (Print)
IS  - 1354-523X (Linking)
VI  - 10
IP  - 2
DP  - 2004 Mar
TI  - Salivary flow and its relationship to oral signs and symptoms in patients with 
      dry eyes.
PG  - 75-80
AB  - OBJECTIVES: The aim of this study was to investigate oral symptoms and clinical 
      parameters in dry eye patients. Subjective reports of the sensation of a dry 
      mouth, salivary flow rates, and clinical parameters of oral disease related to 
      three different types of dry eye patients were examined. SUBJECTS AND METHODS: 
      There were 224 individuals, including dry eye patients and control subjects. The 
      dry eye patients were classified into three types: patients with Sjogren's 
      syndrome (SS-DE), patients without SS-DE (non-SS-DE), and patients with 
      Stevens-Johnson syndrome (SJS-DE). Salivary flow rates were measured using two 
      kinds of sialometry. Subjective and objective oral symptoms and signs were also 
      examined. RESULTS AND CONCLUSION: Over half of the dry eye patients complained of 
      a dry mouth. The flow rates of their stimulated whole saliva and parotid saliva 
      were significantly lower than those of the control groups (P < 0.05, P < 0.01). 
      The sensation of a dry mouth and changes in oral soft tissues, dental caries, and 
      oral Candida frequently occurred in dry eye patients.
FAU - Koseki, M
AU  - Koseki M
AD  - Department of Epidemiology and Public Health, Tokyo Dental College, Chiba, Japan. 
      koseki@tdc.ac.jp
FAU - Maki, Y
AU  - Maki Y
FAU - Matsukubo, T
AU  - Matsukubo T
FAU - Ohashi, Y
AU  - Ohashi Y
FAU - Tsubota, K
AU  - Tsubota K
LA  - eng
PT  - Journal Article
PL  - Denmark
TA  - Oral Dis
JT  - Oral diseases
JID - 9508565
MH  - Adult
MH  - Aged
MH  - Analysis of Variance
MH  - Candidiasis, Oral/complications
MH  - Case-Control Studies
MH  - Cheilitis/complications
MH  - Chi-Square Distribution
MH  - Dental Caries/complications
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Saliva/metabolism
MH  - Secretory Rate
MH  - Sjogren's Syndrome/*complications
MH  - Stevens-Johnson Syndrome/*complications
MH  - Xerophthalmia/*complications/physiopathology
MH  - Xerostomia/*complications
EDAT- 2004/03/05 05:00
MHDA- 2004/04/07 05:00
CRDT- 2004/03/05 05:00
PHST- 2004/03/05 05:00 [pubmed]
PHST- 2004/04/07 05:00 [medline]
PHST- 2004/03/05 05:00 [entrez]
AID - 987 [pii]
AID - 10.1111/j.1354-523x.2003.00987.x [doi]
PST - ppublish
SO  - Oral Dis. 2004 Mar;10(2):75-80. doi: 10.1111/j.1354-523x.2003.00987.x.