PMID- 14997240
OWN - NLM
STAT- MEDLINE
DCOM- 20040401
LR  - 20090529
IS  - 0042-9686 (Print)
IS  - 0042-9686 (Linking)
VI  - 81
IP  - 12
DP  - 2003
TI  - Field trial of applicability of lot quality assurance sampling survey method for 
      rapid assessment of prevalence of active trachoma.
PG  - 877-85
AB  - OBJECTIVE: To test the applicability of lot quality assurance sampling (LQAS) for 
      the rapid assessment of the prevalence of active trachoma. METHODS: Prevalence of 
      active trachoma in six communities was found by examining all children aged 2-5 
      years. Trial surveys were conducted in these communities. A sampling plan 
      appropriate for classifying communities with prevalences < or =20% and > or =40% 
      was applied to the survey data. Operating characteristic and average sample 
      number curves were plotted, and screening test indices were calculated. The 
      ability of LQAS to provide a three-class classification system was investigated. 
      FINDINGS: Ninety-six trial surveys were conducted. All communities with 
      prevalences < or =20% and > or =40% were identified correctly. The method 
      discriminated between communities with prevalences < or =30% and >30%, with 
      sensitivity of 98% (95% confidence interval (CI)=88.2-99.9%), specificity of 
      84.4% (CI=69.9-93.0%), positive predictive value of 87.7% (CI=75.7-94.5%), 
      negative predictive value of 97.4% (CI=84.9-99.9%), and accuracy of 91.7% 
      (CI=83.8-96.1%). Agreement between the three prevalence classes and survey 
      classifications was 84.4% (CI=75.2-90.7%). The time needed to complete the 
      surveys was consistent with the need to complete a survey in one day. CONCLUSION: 
      Lot quality assurance sampling provides a method of classifying communities 
      according to the prevalence of active trachoma. It merits serious consideration 
      as a replacement for the assessment of the prevalence of active trachoma with the 
      currently used trachoma rapid assessment method. It may be extended to provide a 
      multi-class classification method.
FAU - Myatt, Mark
AU  - Myatt M
AD  - Division of Epidemiology, Institute of Ophthalmology, University College London, 
      London, England. mark@myatt.demon.co.uk
FAU - Limburg, Hans
AU  - Limburg H
FAU - Minassian, Darwin
AU  - Minassian D
FAU - Katyola, Damson
AU  - Katyola D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20040301
PL  - Switzerland
TA  - Bull World Health Organ
JT  - Bulletin of the World Health Organization
JID - 7507052
SB  - IM
MH  - Confidence Intervals
MH  - Data Collection
MH  - *Health Surveys
MH  - Humans
MH  - Malawi/epidemiology
MH  - Prevalence
MH  - Quality Assurance, Health Care/*methods
MH  - Sampling Studies
MH  - Sensitivity and Specificity
MH  - Trachoma/*epidemiology
PMC - PMC2572385
EDAT- 2004/03/05 05:00
MHDA- 2004/04/02 05:00
PMCR- 2003/01/01
CRDT- 2004/03/05 05:00
PHST- 2004/03/05 05:00 [pubmed]
PHST- 2004/04/02 05:00 [medline]
PHST- 2004/03/05 05:00 [entrez]
PHST- 2003/01/01 00:00 [pmc-release]
AID - S0042-96862003001200006 [pii]
PST - ppublish
SO  - Bull World Health Organ. 2003;81(12):877-85. Epub 2004 Mar 1.