PMID- 15001287 OWN - NLM STAT- MEDLINE DCOM- 20040406 LR - 20061115 IS - 0300-5712 (Print) IS - 0300-5712 (Linking) VI - 32 IP - 3 DP - 2004 Mar TI - Mapping, profiling and clustering of pressure pain threshold (PPT) in edentulous oral mucosa. PG - 219-28 AB - OBJECTIVES: Edentulous oral mucosa involves different tissue types, various innervation and wound healing process. We hypothesized that pressure pain threshold (PPT) of edentulous oral mucosa varies significantly among different regions. The objective of this study is to examine regional differences and correlations of PPT in edentulous oral mucosa. METHODS: Pain threshold (PPT) was measured at 112 sites in 15 edentulous patients using an electric-controlled pressure algometer. PPT mapping was created by the level of PPT, and PPT clustering was undertaken based on the inter-site correlation of PPT. RESULTS: PPT increased from the anterior to posterior alveolus in both maxilla and mandible, but decreased from the anterior palate to the posterior palate. PPT decreased from the ridge crest to the buccal vestibule. The inter-site difference was four fold within the maxilla and 2.4 fold within the mandible. Principal component analysis applied on PPT inter-site correlation matrix revealed that the maxilla and mandible could be differentiated statistically. The maxilla and mandible were divided into three and four clusters, respectively. CONCLUSION: These results demonstrate that different areas of edentulous oral mucosa have different PPT and that the PPT varies proportionally in selected areas, providing useful diagnostic and therapeutic information in removable prosthodontics and a new opportunity for understanding pain underneath the denture. FAU - Ogawa, T AU - Ogawa T AD - Division of Advanced Prosthodontics, Biomaterials and Hospital Dentistry, Weintraub Center for Reconstructive Biotechnology, UCLA School of Dentistry, P.O. Box 951668, 10833 Le Conte Avenue, B3-088 CHS, Los Angeles, CA 90095-1668, USA. tack@dent.ucla.edu FAU - Tanaka, M AU - Tanaka M FAU - Ogimoto, T AU - Ogimoto T FAU - Okushi, N AU - Okushi N FAU - Koyano, K AU - Koyano K FAU - Takeuchi, K AU - Takeuchi K LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - J Dent JT - Journal of dentistry JID - 0354422 SB - IM MH - Aged MH - Aged, 80 and over MH - Alveolar Process MH - Analysis of Variance MH - Cluster Analysis MH - Dental Stress Analysis MH - Female MH - Humans MH - Male MH - Mandible MH - Maxilla MH - Middle Aged MH - Mouth Mucosa/*innervation/*physiopathology MH - *Mouth, Edentulous MH - Nociceptors MH - Pain Measurement MH - *Pain Threshold MH - Palate, Hard MH - Pressure MH - Principal Component Analysis EDAT- 2004/03/06 05:00 MHDA- 2004/04/07 05:00 CRDT- 2004/03/06 05:00 PHST- 2003/06/17 00:00 [received] PHST- 2003/10/14 00:00 [revised] PHST- 2003/11/11 00:00 [accepted] PHST- 2004/03/06 05:00 [pubmed] PHST- 2004/04/07 05:00 [medline] PHST- 2004/03/06 05:00 [entrez] AID - S0300571203001787 [pii] AID - 10.1016/j.jdent.2003.11.001 [doi] PST - ppublish SO - J Dent. 2004 Mar;32(3):219-28. doi: 10.1016/j.jdent.2003.11.001.