PMID- 15003466
OWN - NLM
STAT- MEDLINE
DCOM- 20041007
LR  - 20081121
IS  - 0021-9975 (Print)
IS  - 0021-9975 (Linking)
VI  - 130
IP  - 2-3
DP  - 2004 Feb-Apr
TI  - Comparison of the pathogenicity of two strains (wild type and vaccine-like) of 
      porcine reproductive and respiratory syndrome virus (PRRSV) in experimentally 
      infected sows.
PG  - 105-11
AB  - The objective of this study was to compare two Korean strains of porcine 
      reproductive and respiratory syndrome virus (PRRSV), namely a wild type (WT) 
      strain and a vaccine-like (VL) strain, in respect of pathogenicity and viral 
      distribution in the tissues. Both strains were of the North American genotype. 
      Two groups of five pregnant sows were infected with either the WT or the VL 
      strain 2 weeks before their expected farrowing date. The WT strain-inoculated 
      sows showed abortion and premature farrowing, whereas the VL strain-inoculated 
      sows remained clinically normal and did not farrow prematurely. Of the 18 
      liveborn piglets from the WT strain-inoculated sows, 14 had interstitial 
      pneumonia. Of the 60 liveborn piglets from the VL strain-inoculated sows, only 
      six had interstitial pneumonia. PRRSV antigen or nucleic acid was detected in 
      48/65 (73.8%) of stillborn and liveborn piglets from the WT strain-inoculated 
      sows, but in only 12/64 (18.8%) of stillborn and liveborn piglets from the VL 
      strain-inoculated sows.
FAU - Cheon, D-S
AU  - Cheon DS
AD  - Department of Veterinary Pathology, College of Veterinary Medicine and School of 
      Agricultural Biotechnology, Seoul National University, San 56-1, Shillim-Dong, 
      Kwanak-Gu, Seoul 151-742, South Korea.
FAU - Chae, C
AU  - Chae C
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Comp Pathol
JT  - Journal of comparative pathology
JID - 0102444
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/blood
MH  - Female
MH  - Heart/virology
MH  - Immunohistochemistry
MH  - In Situ Hybridization
MH  - Infectious Disease Transmission, Vertical/veterinary
MH  - Lung/pathology/virology
MH  - Myocardium/pathology
MH  - Polymorphism, Restriction Fragment Length
MH  - Porcine Reproductive and Respiratory Syndrome/*pathology/transmission
MH  - Porcine respiratory and reproductive syndrome virus/*genetics/*pathogenicity
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*veterinary/virology
MH  - Pregnancy Outcome/veterinary
MH  - Spleen/pathology/virology
MH  - Swine
MH  - Swine Diseases/*virology
EDAT- 2004/03/09 05:00
MHDA- 2004/10/08 09:00
CRDT- 2004/03/09 05:00
PHST- 2002/11/01 00:00 [received]
PHST- 2003/09/01 00:00 [accepted]
PHST- 2004/03/09 05:00 [pubmed]
PHST- 2004/10/08 09:00 [medline]
PHST- 2004/03/09 05:00 [entrez]
AID - S0021997503000926 [pii]
AID - 10.1016/j.jcpa.2003.09.001 [doi]
PST - ppublish
SO  - J Comp Pathol. 2004 Feb-Apr;130(2-3):105-11. doi: 10.1016/j.jcpa.2003.09.001.