PMID- 15017723
OWN - NLM
STAT- MEDLINE
DCOM- 20040722
LR  - 20140625
VI  - 17
IP  - 12
DP  - 2003 Dec
TI  - [The expression of cell adhesion molecule Syndecan-1 and E-candherin in laryngeal 
      cancer].
PG  - 736-8
AB  - OBJECTIVE: To observe Syndecan-1 and E-candherin expression and their 
      relationship with clinico-pathologic factors in primary laryngeal squamous cell 
      carcinoma(LSCC). METHOD: Syndecan-1 and E-candherin proteins were determined with 
      immunohistochemical technique. RESULT: In invasive LSCC the expression of these 
      two adhesion molecules were very similar. Both diminished with decreasing cell 
      differentiation, lacked often in poorly differentiated tumors. And their 
      expression were significantly correlated with each other. CONCLUSION: Our results 
      suggest that Syndecan-1 and E-candherin expression correlates significantly with 
      the histological differentiation grade of the tumors and the tumors size. They 
      may play important roles in the pathogensis and the development of LSCC.
FAU - Li, Yin
AU  - Li Y
AD  - Department of Otolaryngology, Union Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan 430022.
FAU - Yang, Chengzhang
AU  - Yang C
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Lin Chuang Er Bi Yan Hou Ke Za Zhi
JT  - Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology
JID - 9426080
RN  - 0 (Cadherins)
RN  - 0 (Membrane Glycoproteins)
RN  - 0 (Proteoglycans)
RN  - 0 (SDC1 protein, human)
RN  - 0 (Syndecan-1)
RN  - 0 (Syndecans)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cadherins/*analysis
MH  - Carcinoma, Squamous Cell/*chemistry/pathology
MH  - Female
MH  - Glottis
MH  - Humans
MH  - Immunohistochemistry
MH  - Laryngeal Neoplasms/*chemistry/pathology
MH  - Male
MH  - Membrane Glycoproteins/*analysis
MH  - Middle Aged
MH  - Prognosis
MH  - Proteoglycans/*analysis
MH  - Syndecan-1
MH  - Syndecans
EDAT- 2004/03/17 05:00
MHDA- 2004/07/23 05:00
CRDT- 2004/03/17 05:00
PHST- 2004/03/17 05:00 [pubmed]
PHST- 2004/07/23 05:00 [medline]
PHST- 2004/03/17 05:00 [entrez]
PST - ppublish
SO  - Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 Dec;17(12):736-8.