PMID- 15027502
OWN - NLM
STAT- MEDLINE
DCOM- 20041012
LR  - 20220408
IS  - 1054-3406 (Print)
IS  - 1054-3406 (Linking)
VI  - 14
IP  - 1
DP  - 2004 Feb
TI  - Minimal important difference thresholds and the standard error of measurement: is 
      there a connection?
PG  - 97-110
AB  - Several recently published investigations have examined the relationship between 
      the magnitude of the standard error of measurement (SEM) and established 
      thresholds for a minimal clinically important difference (MCID) or a minimal 
      important difference (MID) for change scores on health-related quality of life 
      (HRQOL) or health status measures. These investigations, however, have resulted 
      in differing SEM criteria for the MCID or MID. This study reviews and compares 
      two sets of studies: (1) three investigations using a disease-specific HRQOL 
      measure among patient samples with the chronic disease (heart disease, chronic 
      obstructive pulmonary disease, or asthma) that have consistently demonstrated a 1 
      SEM correspondence with the established MCIDs or MIDs and (2) three 
      investigations among patients referred to physical therapists with back, lower 
      extremity, and neck pain showing that approximately 2.3 SEMs estimated the 
      established MCID standards for three different measures of health status. Chronic 
      disease patients were classified to have a MCID or MID if their global change 
      ratings for the better or the worse were 1, 2, or 3 on a Likert scale ranging 
      from 1 (almost the same, hardly any better, or worse at all) to 7 (a very great 
      deal better or worse). Back pain patients, however, needed average global 
      transition scores of 5, 6, or 7 (a good, a great, or a very great deal better) on 
      the same 7-point Likert scale in order to experience an MCID in their condition. 
      Charting these change levels against their respective SEM-MID criteria provides 
      insight and promise for linking SEM-based criteria to MCID standards for other 
      HRQOL and health status measures.
FAU - Wyrwich, Kathleen W
AU  - Wyrwich KW
AD  - Department of Research Methodology & Health Services Research, Saint Louis 
      University, St. Louis, Missouri 63103, USA. wyrwichk@slu.edu
LA  - eng
GR  - K02 HS11635/HS/AHRQ HHS/United States
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - J Biopharm Stat
JT  - Journal of biopharmaceutical statistics
JID - 9200436
SB  - IM
MH  - *Data Interpretation, Statistical
MH  - *Health Status
MH  - *Health Status Indicators
MH  - Humans
MH  - Research Design/statistics & numerical data
EDAT- 2004/03/19 05:00
MHDA- 2004/10/13 09:00
CRDT- 2004/03/19 05:00
PHST- 2004/03/19 05:00 [pubmed]
PHST- 2004/10/13 09:00 [medline]
PHST- 2004/03/19 05:00 [entrez]
AID - 10.1081/BIP-120028508 [doi]
PST - ppublish
SO  - J Biopharm Stat. 2004 Feb;14(1):97-110. doi: 10.1081/BIP-120028508.