PMID- 1502924 OWN - NLM STAT- MEDLINE DCOM- 19920911 LR - 20171006 IS - 0386-300X (Print) IS - 0386-300X (Linking) VI - 46 IP - 3 DP - 1992 Jun TI - Effect of left atrial plication for the giant left atrium on left ventricular function. PG - 189-93 AB - Left atrial plication (LAP) following Kawazoe's method was performed on eight patients with mitral valve stenosis associated with a giant left atrium. To investigate the effect of LAP particularly on left ventricular function, the preoperative and postoperative left ventricular function in these patients were compared. The data were also compared to that of the non-left atrial plication (non-LAP) group with left atrial dimension of 60 mm or over. In the LAP group, there were significant differences between preoperative and postoperative data in the following parameters; New York Heart Association (NYHA) class, cardiothoracic ratio, mean pulmonary arterial pressure (PAP), left ventricular end-diastolic pressure (LVEDP), left atrial dimension, stroke volume index, ejection fraction and cardiac index. On the contrary, in the non-LAP group, there were significant differences between preoperative and post-operative data in the following two factors; NYHA class and PAP. The size of the left atrium in the non-LAP group remained unchanged over the course of long-term follow-up. Despite severe clinical symptoms and severely reduced cardiac function of the patients in the LAP group, cardiac function in all patients improved satisfactorily. This suggests that left atrial plication has a considerably beneficial effect on left ventricular function, and therefore, may be recommended for patients with a giant left atrium. FAU - Shigenobu, M AU - Shigenobu M AD - Department of Cardiovascular Surgery, Okayama University Medical School, Japan. FAU - Takagaki, M AU - Takagaki M FAU - Kohmoto, T AU - Kohmoto T FAU - Okada, T AU - Okada T FAU - Senoo, Y AU - Senoo Y FAU - Komoto, Y AU - Komoto Y FAU - Teramoto, S AU - Teramoto S LA - eng PT - Journal Article PL - Japan TA - Acta Med Okayama JT - Acta medica Okayama JID - 0417611 SB - IM MH - Adult MH - Female MH - Heart Atria/*pathology/surgery MH - Hemodynamics MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve Stenosis/surgery MH - *Ventricular Function, Left EDAT- 1992/06/01 00:00 MHDA- 1992/06/01 00:01 CRDT- 1992/06/01 00:00 PHST- 1992/06/01 00:00 [pubmed] PHST- 1992/06/01 00:01 [medline] PHST- 1992/06/01 00:00 [entrez] AID - 10.18926/AMO/32667 [doi] PST - ppublish SO - Acta Med Okayama. 1992 Jun;46(3):189-93. doi: 10.18926/AMO/32667.