PMID- 15032367
OWN - NLM
STAT- MEDLINE
DCOM- 20040928
LR  - 20190720
IS  - 0021-9673 (Print)
IS  - 0021-9673 (Linking)
VI  - 1029
IP  - 1-2
DP  - 2004 Mar 12
TI  - Quantitative determination of formaldehyde in cosmetics using a combined 
      solid-phase microextraction-isotope dilution mass spectrometry method.
PG  - 217-22
AB  - Solid-phase microextraction (SPME) in conjunction with isotope dilution mass 
      spectrometry (ID-MS) was employed for the analysis of formaldehyde in cosmetic 
      products. The formaldehyde is derivatized in situ with pentafluorophenyl 
      hydrazine. The formed hydrazone is adsorbed over a 
      poly(dimethylsiloxane)-divinylbenzene-coated fiber and analyzed using gas 
      chromatography-mass spectrometry. The adsorption-time profiles and salting effect 
      were studied. The quantitation was performed by using a stable isotope labeled 
      analogue as an internal standard. The precision, recovery and detection limits 
      were determined with spiked samples. The relative standard deviations from 
      different spiked cosmetic samples were all less than 10% and the recoveries were 
      between 89.00 and 101.23%. The limit of detection was of 0.39 microg/l. Compared 
      with other techniques, the study shown here provides a simple, fast and reliable 
      method for the analysis of formaldehyde in cosmetic products.
FAU - Rivero, Rene Thomas
AU  - Rivero RT
AD  - Analytical Lab, Coty Research and Development Center, 410 American Road, Morris 
      Plains, NJ 07950-2451, USA. rene_rivero@cotyinc.com
FAU - Topiwala, Vinod
AU  - Topiwala V
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Cosmetics)
RN  - 1HG84L3525 (Formaldehyde)
SB  - IM
MH  - Calibration
MH  - Cosmetics/*chemistry
MH  - Formaldehyde/*analysis
MH  - Gas Chromatography-Mass Spectrometry/*methods
MH  - Reference Standards
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
EDAT- 2004/03/23 05:00
MHDA- 2004/09/29 05:00
CRDT- 2004/03/23 05:00
PHST- 2004/03/23 05:00 [pubmed]
PHST- 2004/09/29 05:00 [medline]
PHST- 2004/03/23 05:00 [entrez]
AID - S0021-9673(04)00004-4 [pii]
AID - 10.1016/j.chroma.2003.12.054 [doi]
PST - ppublish
SO  - J Chromatogr A. 2004 Mar 12;1029(1-2):217-22. doi: 10.1016/j.chroma.2003.12.054.