PMID- 15036441
OWN - NLM
STAT- MEDLINE
DCOM- 20040408
LR  - 20131121
IS  - 0379-0738 (Print)
IS  - 0379-0738 (Linking)
VI  - 140
IP  - 2-3
DP  - 2004 Mar 10
TI  - The designer drug situation in Ibiza.
PG  - 195-206
AB  - A total of 137 urine samples and 46 serum samples, corresponding to 154 
      self-confessed designer drugs consumers in Ibiza island, were analyzed for the 
      presence of designer drugs: amphetamine and amphetamine derivatives 
      (methamphetamine, methylenedioxymethamphetamine (MDMA), 
      methylenedioxyethylamphetamine (MDEA), methylenedioxyamphetamine (MDA), 
      p-methoxymethylamphetamine (PMMA), p-methoxyamphetamine (PMA), etc.), ketamine 
      and gamma-hydroxybutyric acid. Among this population, coming both from the 
      forensic clinic and from the emergency room of a hospital, a total of 99 cases 
      were found positive for some designer drug. This study shows the prevalence of 
      methylenedioxymethamphetamine (MDMA) among designer drug users, sole or in 
      association with other drugs. Also, the mixture of MDMA with other designer 
      drugs, ethanol and/or cocaine is shown to be more likely to produce toxic 
      symptoms requiring clinical attendance in a hospital emergency room. These 
      findings along with the consumption history, the concentrations of drugs and 
      metabolites in urine and serum and the toxicological significance for the 
      interpretation of some MDMA metabolites such as 
      4-hydroxy-3-methoxymethamphetamine (HMMA) are discussed in this study.
FAU - Lora-Tamayo, C
AU  - Lora-Tamayo C
AD  - Instituto Nacional de Toxicologia, Ministerio de Justicia, C/ Luis Cabrera 9, 
      Madrid 28002, Spain. c.lora-tamayo@mju.es
FAU - Tena, T
AU  - Tena T
FAU - Rodriguez, A
AU  - Rodriguez A
FAU - Moreno, D
AU  - Moreno D
FAU - Sancho, J R
AU  - Sancho JR
FAU - Ensenat, P
AU  - Ensenat P
FAU - Muela, F
AU  - Muela F
LA  - eng
PT  - Journal Article
PL  - Ireland
TA  - Forensic Sci Int
JT  - Forensic science international
JID - 7902034
RN  - 0 (Designer Drugs)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - *Designer Drugs
MH  - Humans
MH  - N-Methyl-3,4-methylenedioxyamphetamine/blood/urine
MH  - Prevalence
MH  - Spain/epidemiology
MH  - Substance Abuse Detection/methods
MH  - Substance-Related Disorders/blood/*epidemiology/etiology/urine
EDAT- 2004/03/24 05:00
MHDA- 2004/04/09 05:00
CRDT- 2004/03/24 05:00
PHST- 2002/01/16 00:00 [received]
PHST- 2003/11/12 00:00 [accepted]
PHST- 2004/03/24 05:00 [pubmed]
PHST- 2004/04/09 05:00 [medline]
PHST- 2004/03/24 05:00 [entrez]
AID - S0379073803005267 [pii]
AID - 10.1016/j.forsciint.2003.11.021 [doi]
PST - ppublish
SO  - Forensic Sci Int. 2004 Mar 10;140(2-3):195-206. doi: 
      10.1016/j.forsciint.2003.11.021.