PMID- 15068568
OWN - NLM
STAT- MEDLINE
DCOM- 20040901
LR  - 20190513
IS  - 0146-4760 (Print)
IS  - 0146-4760 (Linking)
VI  - 28
IP  - 2
DP  - 2004 Mar
TI  - Application of ORAL.screen saliva drug test for the screening of methamphetamine, 
      MDMA, and MDEA incorporated in hair.
PG  - 132-4
AB  - By the use of a one-step immunoassay drug test for oral fluid, a convenient and 
      fairly sensitive screening method has been devised for methamphetamine (MA), 
      3,4-methylenedioxymethamphetamine (MDMA), and 3,4-methylenedioxyethylamphetamine 
      (MDEA) incorporated in hair. These drugs, in a 10-mg portion of hair, were 
      extracted into 5M HCl/methanol (1:20, v/v), and the extract reconstituted in 100 
      micro L water was assayed with the saliva drug test ORAL.screen trade mark. The 
      limits of detection were 0.5 ng/mg hair for d-MA, 0.8 ng/mg for dl-MDMA, and 1.0 
      ng/mg for dl-MDEA. The results are in good agreement with those of gas 
      chromatography-mass spectrometry (GC-MS) determination. Although all positive 
      results must be confirmed by either GC-MS or a specific alternative methodology, 
      this method provided a simple screening, suitable for drug enforcement purposes, 
      while requiring only a 10-mg hair specimen.
FAU - Miki, Akihiro
AU  - Miki A
AD  - Forensic Science Laboratory, Osaka Prefectural Police Headquarters, 1-3-18 
      Hommachi, Chuo-ward, Osaka 541-0053, Japan. CZD13116@nifty.ne.jp
FAU - Katagi, Munehiro
AU  - Katagi M
FAU - Shima, Noriaki
AU  - Shima N
FAU - Tsuchihashi, Hitoshi
AU  - Tsuchihashi H
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Anal Toxicol
JT  - Journal of analytical toxicology
JID - 7705085
RN  - 0 (Reagent Kits, Diagnostic)
RN  - 44RAL3456C (Methamphetamine)
RN  - 4764-17-4 (3,4-Methylenedioxyamphetamine)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
RN  - ML1I4KK67B (3,4-methylenedioxyethamphetamine)
SB  - IM
MH  - 3,4-Methylenedioxyamphetamine/*analogs & derivatives/*analysis
MH  - Forensic Medicine/methods
MH  - Hair/*chemistry
MH  - Humans
MH  - Immunoassay
MH  - Immunochemistry
MH  - Methamphetamine/*analysis
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*analysis
MH  - *Reagent Kits, Diagnostic
MH  - Saliva/chemistry
MH  - Substance Abuse Detection/*methods
EDAT- 2004/04/08 05:00
MHDA- 2004/09/02 05:00
CRDT- 2004/04/08 05:00
PHST- 2004/04/08 05:00 [pubmed]
PHST- 2004/09/02 05:00 [medline]
PHST- 2004/04/08 05:00 [entrez]
AID - 10.1093/jat/28.2.132 [doi]
PST - ppublish
SO  - J Anal Toxicol. 2004 Mar;28(2):132-4. doi: 10.1093/jat/28.2.132.