PMID- 15073478
OWN - NLM
STAT- MEDLINE
DCOM- 20040715
LR  - 20191108
IS  - 1527-5299 (Print)
IS  - 1527-5299 (Linking)
VI  - 10
IP  - 2 Suppl 2
DP  - 2004 Mar-Apr
TI  - Comparison of impedance cardiography to direct Fick and thermodilution cardiac 
      output determination in pulmonary arterial hypertension.
PG  - 7-10
AB  - Cardiac output (CO) is an important diagnostic and prognostic tool for patients 
      with ventricular dysfunction. Pulmonary hypertension patients undergo invasive 
      right heart catheterization to determine pulmonary vascular and cardiac 
      hemodynamics. Thermodilution (TD) and direct Fick method are the most common 
      methods of CO determination but are costly and may be associated with 
      complications. The latest generation of impedance cardiography (ICG) provides 
      noninvasive estimation of CO and is now validated. The purpose of this study was 
      to compare ICG measurement of CO to TD and direct Fick in pulmonary hypertension 
      patients. Thirty-nine enrolled patients were analyzed: 44% were male and average 
      age was 50.8+/-17.4 years. Results for bias and precision of cardiac index were 
      as follows: ICG vs. Fick (-0.13 L/min/m2 and 0.46 L/min/m2), TD vs. Fick (0.10 
      L/min/m2 and 0.41 L/min/m2), ICG vs. TD (respectively, with a 95% level of 
      agreement between -0.72 and 0.92 L/min/m2; CO correlation of ICG vs. Fick, TD vs. 
      Fick, and ICG vs. TD was 0.84, 0.89, and 0.80, respectively). ICG provides an 
      accurate, useful, and cost-effective method for determining CO in pulmonary 
      hypertension patients, and is a potential tool for following responses to 
      therapeutic interventions.
FAU - Yung, Gordon L
AU  - Yung GL
AD  - Division of Pulmonary and Critical Care Medicine, University of California San 
      Diego Medical Center, San Diego, CA 92103-8373, USA. gyung@ucsd.edu
FAU - Fedullo, Peter F
AU  - Fedullo PF
FAU - Kinninger, Katie
AU  - Kinninger K
FAU - Johnson, Wayne
AU  - Johnson W
FAU - Channick, Richard N
AU  - Channick RN
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Congest Heart Fail
JT  - Congestive heart failure (Greenwich, Conn.)
JID - 9714174
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiac Output/*physiology
MH  - Cardiography, Impedance/*methods
MH  - Female
MH  - Hemodynamics
MH  - Humans
MH  - Hypertension, Pulmonary/*diagnosis/physiopathology
MH  - Male
MH  - Middle Aged
MH  - Oxygen Consumption/physiology
MH  - Thermodilution/*methods
EDAT- 2004/04/10 05:00
MHDA- 2004/07/16 05:00
CRDT- 2004/04/10 05:00
PHST- 2004/04/10 05:00 [pubmed]
PHST- 2004/07/16 05:00 [medline]
PHST- 2004/04/10 05:00 [entrez]
AID - 10.1111/j.1527-5299.2004.03406.x [doi]
PST - ppublish
SO  - Congest Heart Fail. 2004 Mar-Apr;10(2 Suppl 2):7-10. doi: 
      10.1111/j.1527-5299.2004.03406.x.