PMID- 15083084 OWN - NLM STAT- MEDLINE DCOM- 20040511 LR - 20190922 IS - 0740-9303 (Print) IS - 0740-9303 (Linking) VI - 20 IP - 2 DP - 2004 Mar TI - Upper eyelid retraction after glaucoma filtering surgery and topical application of mitomycin C. PG - 144-9 AB - PURPOSE: To describe 3 cases of upper eyelid retraction after glaucoma filtering surgery and topical application of mitomycin C and to highlight possible causes. METHODS: A report of 3 patients, identified over an 8-year interval period, who had development of upper eyelid retraction a few months after undergoing trabeculectomy with mitomycin C in the ipsilateral eye. RESULTS: Testing for Graves disease, including second-generation thyrotropin receptor antibodies (TRAb), was negative in all cases. A complete physical examination was performed by an internist: Orbital and intracranial neuroimaging studies were ordered when necessary, and all were negative. One patient underwent surgical repair of the eyelid retraction and had a satisfactory result. CONCLUSIONS: Upper eyelid retraction after filtering surgery is a rarely reported entity. Muller muscle overaction, independent of Graves disease, is a likely cause and has been pointed out as a possible factor in one previous report. Muller muscle fibrosis, euthyroid Graves disease, and mechanical hindrance to an elevated bleb are other possible factors. FAU - Awwad, Shady T AU - Awwad ST AD - Department of Ophthalmology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. sawwad@eyeweb.org FAU - Ma'luf, Riad N AU - Ma'luf RN FAU - Noureddin, Baha' AU - Noureddin B LA - eng PT - Case Reports PT - Journal Article PL - United States TA - Ophthalmic Plast Reconstr Surg JT - Ophthalmic plastic and reconstructive surgery JID - 8508431 RN - 0 (Antibiotics, Antineoplastic) RN - 50SG953SK6 (Mitomycin) SB - IM MH - Administration, Topical MH - Adolescent MH - Adult MH - Antibiotics, Antineoplastic/*administration & dosage MH - Conjunctiva/drug effects MH - Eyelid Diseases/*etiology/surgery MH - Female MH - Glaucoma, Open-Angle/drug therapy/*surgery MH - Humans MH - Intraocular Pressure MH - Male MH - Mitomycin/*administration & dosage MH - Trabeculectomy/*adverse effects EDAT- 2004/04/15 05:00 MHDA- 2004/05/12 05:00 CRDT- 2004/04/15 05:00 PHST- 2004/04/15 05:00 [pubmed] PHST- 2004/05/12 05:00 [medline] PHST- 2004/04/15 05:00 [entrez] AID - 00002341-200403000-00012 [pii] AID - 10.1097/01.iop.0000115596.80381.80 [doi] PST - ppublish SO - Ophthalmic Plast Reconstr Surg. 2004 Mar;20(2):144-9. doi: 10.1097/01.iop.0000115596.80381.80.