PMID- 1508421
OWN - NLM
STAT- MEDLINE
DCOM- 19920922
LR  - 20131121
IS  - 0161-813X (Print)
IS  - 0161-813X (Linking)
VI  - 13
IP  - 1
DP  - 1992 Spring
TI  - Auditory brainstem evoked potentials (BAEPs) in lead-exposed workers.
PG  - 207-9
AB  - Brainstem Evoked Potentials (BAEPs) were recorded in 49 lead exposed workers, and 
      in a control group of 49 age- and sex-matched subjects, never exposed to 
      neurotoxic substances. The mean duration of lead exposure was 7.4 (SD 5.6) yr. 
      Blood lead concentration was analyzed in the morning of the experimental day 
      (PbBc); an averaged PbB level was based on the levels of the 3 previous years 
      (PbBm). Interpeak latency differences (IPLD) I-V, I-III and III-V were 
      considered. The mean PbBc level was 54.6 (SD 16.1) micrograms/dl while the mean 
      PbBm level was 53.5 (SD 15.9) micrograms/dl. Lead exposed workers showed a 
      significant prolongation of IPLDs. IPLD I-V was longer in the subgroup with PbBm 
      greater than 50 micrograms/dl (4.06 vs 3.98, c.l. 95% 0.00-0.16). These results 
      are consistent with literature data and show that BAEPs may be a sensitive 
      detector of subclinical lead effects on brainstem auditory pathways.
FAU - Discalzi, G L
AU  - Discalzi GL
AD  - Institute of Occupational Health, University of Turin, Italy.
FAU - Capellaro, F
AU  - Capellaro F
FAU - Bottalo, L
AU  - Bottalo L
FAU - Fabbro, D
AU  - Fabbro D
FAU - Mocellini, A
AU  - Mocellini A
LA  - eng
PT  - Journal Article
PL  - Netherlands
TA  - Neurotoxicology
JT  - Neurotoxicology
JID - 7905589
RN  - 2P299V784P (Lead)
SB  - IM
MH  - Adult
MH  - Central Nervous System/*drug effects
MH  - Evoked Potentials, Auditory, Brain Stem/*drug effects
MH  - Female
MH  - Humans
MH  - Lead/*adverse effects
MH  - Male
MH  - *Occupational Exposure
MH  - Sensitivity and Specificity
EDAT- 1992/01/01 00:00
MHDA- 1992/01/01 00:01
CRDT- 1992/01/01 00:00
PHST- 1992/01/01 00:00 [pubmed]
PHST- 1992/01/01 00:01 [medline]
PHST- 1992/01/01 00:00 [entrez]
PST - ppublish
SO  - Neurotoxicology. 1992 Spring;13(1):207-9.