PMID- 15100055
OWN - NLM
STAT- MEDLINE
DCOM- 20040617
LR  - 20161126
IS  - 0006-3002 (Print)
IS  - 0006-3002 (Linking)
VI  - 1655
IP  - 1-3
DP  - 2004 Apr 12
TI  - The bacterial cytochrome cbb3 oxidases.
PG  - 388-99
AB  - Cytochrome cbb(3) oxidases are found almost exclusively in Proteobacteria, and 
      represent a distinctive class of proton-pumping respiratory heme-copper oxidases 
      (HCO) that lack many of the key structural features that contribute to the 
      reaction cycle of the intensely studied mitochondrial cytochrome c oxidase (CcO). 
      Expression of cytochrome cbb(3) oxidase allows human pathogens to colonise anoxic 
      tissues and agronomically important diazotrophs to sustain N(2) fixation. We 
      review recent progress in the biochemical characterisation of these distinctive 
      oxidases that lays the foundation for understanding the basis of their proposed 
      high affinity for oxygen, an apparent degeneracy in their electron input pathways 
      and whether or not they acquired the ability to pump protons independently of 
      other HCOs.
FAU - Pitcher, Robert S
AU  - Pitcher RS
AD  - Centre for Metalloprotein Spectroscopy and Biology, School of Biological 
      Sciences, University of East Anglia, Norwich NR4 7TJ, UK.
FAU - Watmough, Nicholas J
AU  - Watmough NJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - Netherlands
TA  - Biochim Biophys Acta
JT  - Biochimica et biophysica acta
JID - 0217513
RN  - 0 (Ligands)
RN  - 0 (Proton Pumps)
RN  - 42VZT0U6YR (Heme)
RN  - 7U1EE4V452 (Carbon Monoxide)
RN  - EC 1.9.3.- (cbb3 oxidase)
RN  - EC 1.9.3.1 (Electron Transport Complex IV)
SB  - IM
MH  - Bacteria/*enzymology/genetics
MH  - Carbon Monoxide/metabolism
MH  - Electrochemistry
MH  - Electron Spin Resonance Spectroscopy
MH  - Electron Transport Complex IV/*chemistry/genetics/*metabolism
MH  - Gene Expression
MH  - Genes, Bacterial
MH  - Heme/chemistry
MH  - Kinetics
MH  - Ligands
MH  - Proton Pumps/chemistry/metabolism
MH  - Pseudomonas stutzeri/enzymology/genetics
RF  - 100
EDAT- 2004/04/22 05:00
MHDA- 2004/06/18 05:00
CRDT- 2004/04/22 05:00
PHST- 2003/04/08 00:00 [received]
PHST- 2003/09/11 00:00 [revised]
PHST- 2003/09/11 00:00 [accepted]
PHST- 2004/04/22 05:00 [pubmed]
PHST- 2004/06/18 05:00 [medline]
PHST- 2004/04/22 05:00 [entrez]
AID - S0005272803002123 [pii]
AID - 10.1016/j.bbabio.2003.09.017 [doi]
PST - ppublish
SO  - Biochim Biophys Acta. 2004 Apr 12;1655(1-3):388-99. doi: 
      10.1016/j.bbabio.2003.09.017.