PMID- 15101494 OWN - NLM STAT- MEDLINE DCOM- 20040702 LR - 20191108 IS - 1098-3597 (Print) IS - 1873-4480 (Linking) VI - 5 IP - 4 DP - 2003 TI - Esophageal complications of gastroesophageal reflux disease: presentation, diagnosis, management, and outcomes. PG - 41-8; discussion 49-50 AB - The esophageal complications of gastroesophageal reflux disease include peptic esophageal erosion and ulceration, peptic esophageal strictures, and Barrett's esophagus. Endoscopy is the diagnostic procedure of choice for the initial evaluation of lesions. For most patients, symptoms can be controlled with proton pump inhibitor (PPI) therapy. PPIs are also highly effective for healing esophageal erosions and ulcerations and for preventing recurrence of peptic esophageal strictures. Because Barrett's esophagus predisposes individuals to esophageal adenocarcinoma, these patients are advised to have regular endoscopic surveillance to detect early, curable neoplasms. FAU - Spechler, Stuart Jon AU - Spechler SJ AD - Division of Gastroenterology, Dallas Veterans Affairs Medical Center, Texas 75216, USA. SJSpechler@aol.com LA - eng PT - Journal Article PT - Review PL - United States TA - Clin Cornerstone JT - Clinical cornerstone JID - 9816002 RN - 0 (Proton Pump Inhibitors) SB - IM MH - Barrett Esophagus/etiology MH - Esophageal Diseases/diagnosis/drug therapy/*etiology/surgery MH - Esophageal Stenosis/etiology MH - Esophagoscopy MH - Gastroesophageal Reflux/*complications/pathology MH - Humans MH - Proton Pump Inhibitors RF - 46 EDAT- 2004/04/23 05:00 MHDA- 2004/07/03 05:00 CRDT- 2004/04/23 05:00 PHST- 2004/04/23 05:00 [pubmed] PHST- 2004/07/03 05:00 [medline] PHST- 2004/04/23 05:00 [entrez] AID - S1098-3597(03)90098-6 [pii] AID - 10.1016/s1098-3597(03)90098-6 [doi] PST - ppublish SO - Clin Cornerstone. 2003;5(4):41-8; discussion 49-50. doi: 10.1016/s1098-3597(03)90098-6.