PMID- 15102417
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20040803
LR  - 20191108
IS  - 1090-3801 (Print)
IS  - 1090-3801 (Linking)
VI  - 1
IP  - 2
DP  - 1997
TI  - Morphine-3-glucuronide prevents tolerance to morphine-6-glucuronide in mice.
PG  - 161-4
AB  - Daily subcutaneous (s.c.) pretreatment with morphine-3-glucuronide (6 mg/kg) was 
      found to reduce morphine-6-glucuronide (4 mg/kg s.c.)-induced antinociception, 
      with no decrease in the effect over 5 days. Morphine-6-glucuronide administration 
      (4 mg/kg s.c.) on Day 6, without morphine-3-glucorinide pretreatment, results in 
      a significant increase in antinociception (from 24% on Day 5 to 70%; p< or 
      =0.05). Morphine-3-glucuronide may prevent tolerance to morphine-6-glucuronide by 
      reducing morphine-6-glucuronide-induced antinociception.
FAU - Faura, C C
AU  - Faura CC
AD  - Departamento de Farmacologia y Terapeutica, Universidad Miguel Hernandez, 
      Alicante, Spain.
FAU - Olaso, M J
AU  - Olaso MJ
FAU - Horga, J F
AU  - Horga JF
LA  - eng
PT  - Journal Article
PL  - England
TA  - Eur J Pain
JT  - European journal of pain (London, England)
JID - 9801774
EDAT- 1997/01/01 00:00
MHDA- 1997/01/01 00:01
CRDT- 1997/01/01 00:00
PHST- 1997/03/05 00:00 [received]
PHST- 1997/06/17 00:00 [accepted]
PHST- 1997/01/01 00:00 [pubmed]
PHST- 1997/01/01 00:01 [medline]
PHST- 1997/01/01 00:00 [entrez]
AID - S1090380197900744 [pii]
AID - 10.1016/s1090-3801(97)90074-4 [doi]
PST - ppublish
SO  - Eur J Pain. 1997;1(2):161-4. doi: 10.1016/s1090-3801(97)90074-4.