PMID- 1510464
OWN - NLM
STAT- MEDLINE
DCOM- 19920924
LR  - 20191028
IS  - 0195-6663 (Print)
IS  - 0195-6663 (Linking)
VI  - 18
IP  - 3
DP  - 1992 Jun
TI  - Experience with a macronutrient source influences subsequent macronutrient 
      selection.
PG  - 223-32
AB  - We examined the influence of experience with a macronutrient on subsequent 
      macronutrient selection. For 4 days, rats ate chow, or chow and a single 
      macronutrient source. They then had simultaneous access to protein, carbohydrate 
      (CHO) and fat sources, according to a standard macronutrient self-selection 
      paradigm. When selecting among the macronutrient sources, rats pre-exposed to CHO 
      ate more CHO, and those pre-exposed to fat ate more fat, relative to the other 
      groups. Rats pre-exposed to protein ate more protein than did those pre-exposed 
      to CHO or fat but not more than those that received no macronutrient 
      pre-exposure. These selection patterns persisted for at least 12 days, when the 
      test was ended because of the low protein intakes and poor growth of the rats 
      pre-exposed to the CHO and fat sources. After 34 days of recovery with only chow 
      to eat, the rats were again allowed to choose among the three macronutrients, and 
      their patterns of selection were essentially unchanged. Similar results were 
      found in a second experiment in which a 5-day interval was interposed between 
      macronutrient pre-exposure and macronutrient selection. These findings show that 
      experience with the macronutrients typically used in self-selection experiments 
      can have a large, long-lasting, and sometimes detrimental effect on subsequent 
      food selection by rats. Prior experience can be a more powerful influence than 
      nutritional wisdom in determining the rat's food choice.
FAU - Reed, D R
AU  - Reed DR
AD  - Yale University.
FAU - Friedman, M I
AU  - Friedman MI
FAU - Tordoff, M G
AU  - Tordoff MG
LA  - eng
GR  - DK-36339/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - England
TA  - Appetite
JT  - Appetite
JID - 8006808
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Dietary Fats)
SB  - IM
MH  - Animals
MH  - Dietary Carbohydrates/*administration & dosage
MH  - Dietary Fats/*administration & dosage
MH  - Energy Intake
MH  - *Food Preferences
MH  - Male
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Weight Gain
EDAT- 1992/06/01 00:00
MHDA- 1992/06/01 00:01
CRDT- 1992/06/01 00:00
PHST- 1992/06/01 00:00 [pubmed]
PHST- 1992/06/01 00:01 [medline]
PHST- 1992/06/01 00:00 [entrez]
AID - 10.1016/0195-6663(92)90199-g [doi]
PST - ppublish
SO  - Appetite. 1992 Jun;18(3):223-32. doi: 10.1016/0195-6663(92)90199-g.