PMID- 15107635
OWN - NLM
STAT- MEDLINE
DCOM- 20040706
LR  - 20190911
IS  - 0148-5717 (Print)
IS  - 0148-5717 (Linking)
VI  - 31
IP  - 5
DP  - 2004 May
TI  - Seroprevalence of herpes simplex virus-2 in suburban primary care offices in the 
      United States.
PG  - 311-6
AB  - OBJECTIVE: The objective of this study was to estimate herpes simplex virus-2 
      (HSV-2) seroprevalence from a weighted sample of adults attending relatively 
      affluent, suburban primary care physician (PCP) offices. GOAL: Many PCPs in 
      relatively affluent areas do not believe national estimates of HSV-2 
      seroprevalence are representative of their patient populations. This study aimed 
      to measure HSV-2 seroprevalence in these patient populations. STUDY DESIGN: We 
      conducted a cross-sectional study with approximately 5400 individuals aged 18 to 
      59 years. Individuals were recruited at 36 PCP offices in 6 U.S. cities and 
      tested for HSV-2 using Focus enzyme-linked immunosorbent assay. A 
      computer-assisted questionnaire was used to assess risk behaviors associated with 
      genital herpes. RESULTS: Among 5452 individuals who provided an analyzable blood 
      sample, the overall weighted HSV-2 seroprevalence was 25.5% (95% confidence 
      interval, 20.2-30.8%). Only 11.9% of HSV-2-seropositive patients reported a 
      history of genital herpes. CONCLUSIONS: Results illustrate the need for greater 
      suburban PCP and patient awareness of the high HSV-2 seroprevalence in this 
      setting.
FAU - Leone, Peter
AU  - Leone P
AD  - University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
FAU - Fleming, Douglas T
AU  - Fleming DT
FAU - Gilsenan, Alicia W
AU  - Gilsenan AW
FAU - Li, Lei
AU  - Li L
FAU - Justus, Scott
AU  - Justus S
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Sex Transm Dis
JT  - Sexually transmitted diseases
JID - 7705941
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Age Distribution
MH  - Cross-Sectional Studies
MH  - Female
MH  - Herpes Genitalis/blood/*epidemiology/etiology
MH  - Herpesvirus 2, Human/*isolation & purification
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Primary Health Care/*statistics & numerical data
MH  - Risk Factors
MH  - Risk-Taking
MH  - Seroepidemiologic Studies
MH  - Sex Distribution
MH  - Sexual Behavior
MH  - Suburban Health/*statistics & numerical data
MH  - Surveys and Questionnaires
MH  - United States/epidemiology
EDAT- 2004/04/27 05:00
MHDA- 2004/07/09 05:00
CRDT- 2004/04/27 05:00
PHST- 2004/04/27 05:00 [pubmed]
PHST- 2004/07/09 05:00 [medline]
PHST- 2004/04/27 05:00 [entrez]
AID - 00007435-200405000-00010 [pii]
AID - 10.1097/01.olq.0000123651.84697.d6 [doi]
PST - ppublish
SO  - Sex Transm Dis. 2004 May;31(5):311-6. doi: 10.1097/01.olq.0000123651.84697.d6.