PMID- 15118283
OWN - NLM
STAT- MEDLINE
DCOM- 20041109
LR  - 20190819
IS  - 1346-9843 (Print)
IS  - 1346-9843 (Linking)
VI  - 68
IP  - 5
DP  - 2004 May
TI  - Analysis of chronic heart failure registry in the Tohoku district: third year 
      follow-up.
PG  - 427-34
AB  - BACKGROUND: Because the real prognosis of Japanese patients with chronic heart 
      failure (CHF) is still unknown, the aim of the present study was to clarify the 
      prognosis and predictors for mortality of CHF patients using the Chronic Heart 
      failure Analysis and Registry in Tohoku district (CHART). METHODS AND RESULTS: As 
      of February 2003, 1,154 stable CHF patients with optimum standard therapy have 
      been enrolled in the registry since February 2000 and of these, 175 died of some 
      cause during the follow-up period (mean follow-up period, 1.9+/-0.9 years), 
      giving 1- and 3-year all-cause mortality rates of 7.3% and 20.9%, respectively. 
      Multivariate analysis showed that age at entry, diabetes, ventricular 
      tachycardia, plasma concentration of brain natriuretic peptide (BNP), New York 
      Heart Association (NYHA) functional class and rural residence were significantly 
      associated with all-cause mortality (hazard ratio: 1.028, 1.940, 1.650, 1.001, 
      1.713, and 2.226). The 1-year all-cause mortality rates of CHF patients with a 
      left ventricular ejection fraction <25%, left ventricular end-diastolic diameter 
      > or =60 mm, BNP > or =500 pg/ml, NYHA > or = III, or with underlying coronary 
      artery disease were 15.0%, 11.4%, 16.8%, 16.3%, and 10.8%, respectively. 
      CONCLUSIONS: The prognosis of Japanese CHF patients with these predictors remains 
      poor. A stratified approach is necessary to improve their survival and quality of 
      life.
FAU - Shiba, Nobuyuki
AU  - Shiba N
AD  - Department of Cardiovascular Medicine, Tohoku University Graduate School of 
      Medicine, Sendai, Japan.
FAU - Watanabe, Jun
AU  - Watanabe J
FAU - Shinozaki, Tsuyoshi
AU  - Shinozaki T
FAU - Koseki, Yoshito
AU  - Koseki Y
FAU - Sakuma, Masahito
AU  - Sakuma M
FAU - Kagaya, Yutaka
AU  - Kagaya Y
FAU - Shirato, Kunio
AU  - Shirato K
CN  - CHART Investigators
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Aged
MH  - Cardiac Output, Low/blood/etiology/*mortality/physiopathology
MH  - Chronic Disease
MH  - Coronary Disease/complications
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Japan
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Natriuretic Peptide, Brain/blood
MH  - Predictive Value of Tests
MH  - Prognosis
MH  - *Registries
MH  - Risk Factors
MH  - Severity of Illness Index
MH  - Stroke Volume
EDAT- 2004/05/01 05:00
MHDA- 2004/11/13 09:00
CRDT- 2004/05/01 05:00
PHST- 2004/05/01 05:00 [pubmed]
PHST- 2004/11/13 09:00 [medline]
PHST- 2004/05/01 05:00 [entrez]
AID - 10.1253/circj.68.427 [doi]
PST - ppublish
SO  - Circ J. 2004 May;68(5):427-34. doi: 10.1253/circj.68.427.