PMID- 15118299
OWN - NLM
STAT- MEDLINE
DCOM- 20041109
LR  - 20190819
IS  - 1346-9843 (Print)
IS  - 1346-9843 (Linking)
VI  - 68
IP  - 5
DP  - 2004 May
TI  - Gitelman's syndrome with exercise-induced ventricular tachycardia.
PG  - 509-11
AB  - A 62-year-old female with palpitations was admitted to hospital where she 
      recorded 12,299 monofocal ventricular premature contractions (VPCs) in 24 h and 
      nonsustained ventricular tachycardia (VT) on exertion. She had hypokalemia with 
      renal potassium wasting, a chloride-resistant metabolic alkalosis, elevated 
      plasma renin, elevated plasma aldosterone (relative to the serum K 
      concentration), hypomagnesemia with renal magnesium wasting, decreased urine 
      calcium excretion, and normal blood pressure. The hypokalemia and hypomagnesemia 
      were thought to have precipitated the VT. The coronary angiogram showed normal 
      coronary arteries; however, the left ventriculogram revealed akinesis of the 
      posterolateral wall. Because the VT could not be induced by programmed electrical 
      stimulation either before or during intravenous administration of isoproterenol, 
      the VPC with the same QRS morphology as the VT became the target of 
      radiofrequency catheter ablation (RF-CA). Intracardiac mapping showed that the 
      earliest activation site was situated in the asynergic area of the left ventricle 
      (LV) and radiofrequency catheter ablation directed at the LV asynergy area 
      completely eliminated the VPCs without any complications. During the follow-up 
      period (6 months), she was free from palpitation and VT was not clinically 
      documented.
FAU - Nakane, Eisaku
AU  - Nakane E
AD  - Third Division, Department of Internal Medicine, Osaka Medical College, Osaka, 
      Japan.
FAU - Kono, Tatsuji
AU  - Kono T
FAU - Sasaki, Yosio
AU  - Sasaki Y
FAU - Tokaji, Yasunobu
AU  - Tokaji Y
FAU - Ito, Takahide
AU  - Ito T
FAU - Sohmiya, Koichi
AU  - Sohmiya K
FAU - Sakai, Yasuhiko
AU  - Sakai Y
FAU - Suwa, Michihiro
AU  - Suwa M
FAU - Tanaka, Takao
AU  - Tanaka T
FAU - Nisimura, Hikaru
AU  - Nisimura H
FAU - Kitaura, Yasusi
AU  - Kitaura Y
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
MH  - *Catheter Ablation
MH  - Electrocardiography
MH  - *Exercise
MH  - Female
MH  - Humans
MH  - Hypokalemia/*complications
MH  - Magnesium Deficiency/*complications
MH  - Middle Aged
MH  - Radionuclide Ventriculography
MH  - Syndrome
MH  - Tachycardia, Ventricular/diagnosis/*etiology/*therapy
EDAT- 2004/05/01 05:00
MHDA- 2004/11/13 09:00
CRDT- 2004/05/01 05:00
PHST- 2004/05/01 05:00 [pubmed]
PHST- 2004/11/13 09:00 [medline]
PHST- 2004/05/01 05:00 [entrez]
AID - 10.1253/circj.68.509 [doi]
PST - ppublish
SO  - Circ J. 2004 May;68(5):509-11. doi: 10.1253/circj.68.509.