PMID- 15124152
OWN - NLM
STAT- MEDLINE
DCOM- 20041019
LR  - 20041117
IS  - 0010-440X (Print)
IS  - 0010-440X (Linking)
VI  - 45
IP  - 3
DP  - 2004 May-Jun
TI  - Patient characteristics and diagnostic discrepancy in first-episode psychosis.
PG  - 213-8
AB  - Despite the operational criteria in diagnostic systems there is still marked 
      diversity between clinical and research diagnoses in populations with psychotic 
      disorders. The objective of the current study was to explore the association of 
      patient-related factors with diagnostic agreement between clinical diagnoses and 
      Schedules for Clinical Assessment in Neuropsychiatry (SCAN-2) diagnoses in 
      first-episode psychosis. The sample included 80 consecutive patients. As 
      explanatory variables we used demographic characteristics (gender, age, living 
      circumstances, education, and social activities), measures of psychopathology 
      (Positive and Negative Symptom scale [PANSS], Hamilton Depression Scale, Global 
      Assessment of Functioning Scale [GAF], and Strauss-Carpenter Scale), duration of 
      untreated psychosis, and diagnostic category according to SCAN-2 interview. The 
      overall agreement value between the clinical and research diagnoses was 0.55 
      (kappa). In the whole sample low scores on the PANSS negative subscale, low level 
      of education, and high score on the PANSS item for delusions predicted diagnostic 
      discrepancy. Acute and transient psychotic disorder as a research diagnosis 
      predicted diagnostic agreement. In the schizophrenia group, young age and lack of 
      social activities predicted diagnostic agreement. Bivariate comparisons of 
      treatment compliance, perceived medication side effects, or negative attitudes 
      towards treatment showed no associations with diagnostic agreement. The results 
      confirm some of the findings in the few previous studies. The diagnosis of 
      schizophrenia is likely to be delayed and there is a need for further education 
      with clinicians in recognizing the symptoms of schizophrenia.
FAU - Kampman, Olli
AU  - Kampman O
AD  - University of Tampere, Medical School, Finland.
FAU - Kiviniemi, Paivi
AU  - Kiviniemi P
FAU - Koivisto, Elina
AU  - Koivisto E
FAU - Vaananen, Juha
AU  - Vaananen J
FAU - Kilkku, Nina
AU  - Kilkku N
FAU - Leinonen, Esa
AU  - Leinonen E
FAU - Lehtinen, Klaus
AU  - Lehtinen K
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Compr Psychiatry
JT  - Comprehensive psychiatry
JID - 0372612
SB  - IM
MH  - Adult
MH  - Age Factors
MH  - Diagnosis, Differential
MH  - Educational Status
MH  - Female
MH  - Humans
MH  - Interview, Psychological
MH  - Male
MH  - Multivariate Analysis
MH  - Predictive Value of Tests
MH  - Psychiatric Status Rating Scales
MH  - Psychotic Disorders/*diagnosis
MH  - Schizophrenia/diagnosis
MH  - Sensitivity and Specificity
MH  - Social Support
EDAT- 2004/05/05 05:00
MHDA- 2004/10/20 09:00
CRDT- 2004/05/05 05:00
PHST- 2004/05/05 05:00 [pubmed]
PHST- 2004/10/20 09:00 [medline]
PHST- 2004/05/05 05:00 [entrez]
AID - S0010440X04000173 [pii]
AID - 10.1016/j.comppsych.2004.02.002 [doi]
PST - ppublish
SO  - Compr Psychiatry. 2004 May-Jun;45(3):213-8. doi: 10.1016/j.comppsych.2004.02.002.