PMID- 15125264 OWN - NLM STAT- MEDLINE DCOM- 20040525 LR - 20161124 IS - 1405-9940 (Print) IS - 1665-1731 (Linking) VI - 74 IP - 1 DP - 2004 Jan-Mar TI - [Assessment of diastolic function in Chagas' disease with pulsed doppler tissue imaging]. PG - 31-8 AB - Diastolic function is involved early during the undetermined form of Chagas' disease (Ch). Pulsed Doppler tissue imaging (DTI) is a new technique to evaluate diastolic function recording myocardial velocities in the longitudinal axis. To evaluate the relevance of DTI in patients with Ch, we studied, with Doppler and echocardiography, 49 patients (average age 49 +/- 12 years) and 20 normal subjects (average age 45 +/- 15 years) as a control group (C). Patients were divided in four groups according to the pattern of their mitral and pulmonary vein flows: Normal diastolic function (N), prolonged relaxation (PR), pseudonormal (PN) and restrictive (R). Peak velocity of the E wave of the lateral mitral annulus (Ea) was diminished in PR, PN, and R patients (0.11 +/- 0.02 m/s, 0.10 +/- 0.02 m/s and 0.12 +/- 0.06 m/s, respectively) as compared to group C (0.18 +/- 0.07 m/s, p < 0.01) but not with respect to group N (0.15 +/- 0.03 m/s, N.S.). In this latter group only peak E velocity of transmitral flow/Ea ratio was useful to detect diastolic abnormalities as compared to group C (4.92 +/- 0.98 vs 4.14 +/- 1.26, p < 0.05). DTI was useful in the assessment of diastolic function in Ch, including those patients in whom mitral and pulmonary vein flows were normal. FAU - Migliore, Ricardo A AU - Migliore RA AD - Servicio de Cardiologia, Hospital Eva Peron, San Martin, Provincia de Buenos Aires. rmigliore@intramed.net.ar FAU - Adaniya, Maria E AU - Adaniya ME FAU - Tamagusuku, Horacio AU - Tamagusuku H FAU - Lapuente, Alberto AU - Lapuente A LA - spa PT - Comparative Study PT - Journal Article TT - Utilidad del Doppler tisular pulsado en la valoracion de la funcion diastolica en la enfermedad de Chagas. PL - Mexico TA - Arch Cardiol Mex JT - Archivos de cardiologia de Mexico JID - 101126728 SB - IM MH - Adult MH - Case-Control Studies MH - Chagas Cardiomyopathy/*diagnostic imaging/physiopathology MH - Diastole/physiology MH - Echocardiography, Doppler, Pulsed/*methods MH - Female MH - Heart Ventricles/*diagnostic imaging/physiopathology MH - Humans MH - Male MH - Middle Aged MH - Prospective Studies MH - Ventricular Function/*physiology EDAT- 2004/05/06 05:00 MHDA- 2004/05/27 05:00 CRDT- 2004/05/06 05:00 PHST- 2004/05/06 05:00 [pubmed] PHST- 2004/05/27 05:00 [medline] PHST- 2004/05/06 05:00 [entrez] PST - ppublish SO - Arch Cardiol Mex. 2004 Jan-Mar;74(1):31-8.