PMID- 15125723
OWN - NLM
STAT- MEDLINE
DCOM- 20040917
LR  - 20041117
IS  - 0147-8389 (Print)
IS  - 0147-8389 (Linking)
VI  - 27
IP  - 5
DP  - 2004 May
TI  - Basic assessment of paced activation sequence mapping: implications for practical 
      use.
PG  - 651-6
AB  - Some experiences support the use of atrial paced activation sequence mapping, but 
      there is no systematic study assessing its spatial resolution, reproducibility, 
      and influence of pacing parameters. The aim of this study was to evaluate these 
      issues by using a 24-pole catheter positioned at the atrial aspect of the 
      tricuspid and mitral annuli in 15 patients. Bipolar pacing was performed at two 
      sites (right and left atria), 2 cycle lengths (300 and 500 ms) and two outputs 
      (twice and tenfold the late diastolic threshold voltage for 2-ms pulses). The 
      elapsed time between the atrial activation at the two dipoles adjacent to the 
      pacing dipole (activation time [AT]) was measured during each pacing sequence. 
      Changes in cycle length did not modify the AT. The increase in voltage slightly 
      modified the AT (maximum -2 ms at the RA; 95% CI -3 to -1 ms) due to a greater 
      shortening of the conduction time to the dipole located next to the anode. The 
      95% limits of the intraobserver and interobserver agreements in the AT 
      measurement were -2 to 3 ms and -3 to 3 ms, respectively. The spatial resolution 
      was studied in ten patients by measuring the AT during pacing from each dipole of 
      a 20-pole catheter with a 1-3-1 mm interelectrode distance. The mean AT change 
      was 10 +/- 4 ms per 6 mm of pacing site displacement (95% CI 8-11 ms, range 
      2.5-20 ms). In conclusion, paced atrial activation sequence analysis is 
      reproducible, accurate, and relatively independent of pacing parameters.
FAU - Perez-Castellano, Nicasio
AU  - Perez-Castellano N
AD  - Unit of Arrhythmias, Cardiovascular Institute, San Carlos University Hospital, 
      Madrid, Spain. npc@jet.es
FAU - Almendral, Jesus
AU  - Almendral J
FAU - Villacastin, Julian
AU  - Villacastin J
FAU - Arenal, Angel
AU  - Arenal A
FAU - Gonzalez, Sergio
AU  - Gonzalez S
FAU - Moreno, Javier
AU  - Moreno J
FAU - Morales, Ricardo
AU  - Morales R
FAU - Macaya, Carlos
AU  - Macaya C
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Pacing Clin Electrophysiol
JT  - Pacing and clinical electrophysiology : PACE
JID - 7803944
SB  - IM
MH  - Cardiac Pacing, Artificial/*standards
MH  - Electrocardiography
MH  - *Heart Atria
MH  - Humans
MH  - Reproducibility of Results
EDAT- 2004/05/06 05:00
MHDA- 2004/09/21 05:00
CRDT- 2004/05/06 05:00
PHST- 2004/05/06 05:00 [pubmed]
PHST- 2004/09/21 05:00 [medline]
PHST- 2004/05/06 05:00 [entrez]
AID - PACE501 [pii]
AID - 10.1111/j.1540-8159.2004.00501.x [doi]
PST - ppublish
SO  - Pacing Clin Electrophysiol. 2004 May;27(5):651-6. doi: 
      10.1111/j.1540-8159.2004.00501.x.