PMID- 15126407
OWN - NLM
STAT- MEDLINE
DCOM- 20050104
LR  - 20191108
IS  - 0016-6731 (Print)
IS  - 0016-6731 (Linking)
VI  - 166
IP  - 4
DP  - 2004 Apr
TI  - Evolutionary relationships of major histocompatibility complex class I genes in 
      simian primates.
PG  - 1897-907
AB  - New World monkeys (NWMs) occupy a critical phylogenetic position in elucidating 
      the evolutionary process of major histocompatibility complex (MHC) class I genes 
      in primates. From three subfamilies of Aotinae, Cebinae, and Atelinae, the 
      5'-flanking regions of 18 class I genes are obtained and phylogenetically 
      examined in terms of Alu/LINE insertion elements as well as the nucleotide 
      substitutions. Two pairs of genes from Aotinae and Atelinae are clearly 
      orthologous to human leukocyte antigen (HLA) -E and -F genes. Of the remaining 14 
      genes, 8 belong to the distinct group B, together with HLA-B and -C, to the 
      exclusion of all other HLA class I genes. These NWM genes are classified into 
      four groups, designated as NWM-B1, -B2, -B3, and -B4. Of these, NWM-B2 is 
      orthologous to HLA-B/C. Also, orthologous relationships of NWM-B1, -B2, and -B3 
      exist among different families of Cebidae and Atelidae, which is in sharp 
      contrast to the genus-specific gene organization within the subfamily 
      Callitrichinae. The other six genes belong to the distinct group G. However, a 
      clade of these NWM genes is almost equally related to HLA-A, -J, -G, and -K, and 
      there is no evidence for their orthologous relationships to HLA-G. It is argued 
      that class I genes in simian primates duplicated extensively in their common 
      ancestral lineage and that subsequent evolution in descendant species has been 
      facilitated mainly by independent loss of genes.
FAU - Sawai, Hiromi
AU  - Sawai H
AD  - Department of Biosystems Science, Graduate University for Advanced Studies 
      (Sokendai), Hayama, Kanagawa 240-0193, Japan.
FAU - Kawamoto, Yoshi
AU  - Kawamoto Y
FAU - Takahata, Naoyuki
AU  - Takahata N
FAU - Satta, Yoko
AU  - Satta Y
LA  - eng
SI  - GENBANK/AB113090
SI  - GENBANK/AB113091
SI  - GENBANK/AB113092
SI  - GENBANK/AB113093
SI  - GENBANK/AB113094
SI  - GENBANK/AB113095
SI  - GENBANK/AB113096
SI  - GENBANK/AB113097
SI  - GENBANK/AB113098
SI  - GENBANK/AB113099
SI  - GENBANK/AB113100
SI  - GENBANK/AB113101
SI  - GENBANK/AB113102
SI  - GENBANK/AB113103
SI  - GENBANK/AB113104
SI  - GENBANK/AB113105
SI  - GENBANK/AB113106
SI  - GENBANK/AB113107
SI  - GENBANK/AB113108
SI  - GENBANK/AB113109
SI  - GENBANK/AB113110
SI  - GENBANK/AB113111
SI  - GENBANK/AB113112
SI  - GENBANK/AB113202
SI  - GENBANK/AB113203
SI  - GENBANK/AB113204
SI  - GENBANK/AB113205
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Genetics
JT  - Genetics
JID - 0374636
RN  - 0 (DNA Primers)
SB  - IM
MH  - 5' Flanking Region/genetics
MH  - Animals
MH  - Base Sequence
MH  - Cebidae/*genetics
MH  - Cluster Analysis
MH  - DNA Primers
MH  - *Evolution, Molecular
MH  - Genes, MHC Class I/*genetics
MH  - Long Interspersed Nucleotide Elements/genetics
MH  - Molecular Sequence Data
MH  - *Phylogeny
MH  - Sequence Analysis, DNA
MH  - Species Specificity
PMC - PMC1470823
EDAT- 2004/05/06 05:00
MHDA- 2005/01/05 09:00
PMCR- 2004/07/01
CRDT- 2004/05/06 05:00
PHST- 2004/05/06 05:00 [pubmed]
PHST- 2005/01/05 09:00 [medline]
PHST- 2004/05/06 05:00 [entrez]
PHST- 2004/07/01 00:00 [pmc-release]
AID - 166/4/1897 [pii]
AID - 10.1534/genetics.166.4.1897 [doi]
PST - ppublish
SO  - Genetics. 2004 Apr;166(4):1897-907. doi: 10.1534/genetics.166.4.1897.