PMID- 1514780
OWN - NLM
STAT- MEDLINE
DCOM- 19920925
LR  - 20211203
IS  - 0364-5134 (Print)
IS  - 0364-5134 (Linking)
VI  - 31
IP  - 6
DP  - 1992 Jun
TI  - Idiopathic childhood stroke is associated with human leukocyte antigen (HLA)-B51.
PG  - 675-7
AB  - We report four children with idiopathic stroke syndromes who were assayed for 
      human leukocyte antigen (HLA) class I markers and found to have HLA-B51 in 
      common. This finding suggests that there may be a genetic predisposition for 
      "idiopathic" childhood stroke, and host factors, possibly in concert with 
      environmental factors or viruses, may play a major role in the mechanism of 
      unexplained occlusion of the cerebral vasculature in children.
FAU - Mintz, M
AU  - Mintz M
AD  - Department of Neurosciences, University of Medicine and Dentistry-New Jersey 
      Medical School, Newark 07103.
FAU - Epstein, L G
AU  - Epstein LG
FAU - Koenigsberger, M R
AU  - Koenigsberger MR
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Ann Neurol
JT  - Annals of neurology
JID - 7707449
RN  - 0 (HLA-B Antigens)
RN  - 0 (HLA-B51 Antigen)
SB  - IM
MH  - Cerebrovascular Disorders/ethnology/*genetics/immunology
MH  - Child
MH  - Child, Preschool
MH  - Disease Susceptibility/immunology
MH  - Female
MH  - Gene Frequency
MH  - *Genes, MHC Class I
MH  - Genetic Predisposition to Disease
MH  - HLA-B Antigens/*analysis
MH  - HLA-B51 Antigen
MH  - Hispanic or Latino/genetics
MH  - Humans
MH  - Infant
MH  - Male
MH  - Vascular Diseases/genetics
EDAT- 1992/06/01 00:00
MHDA- 1992/06/01 00:01
CRDT- 1992/06/01 00:00
PHST- 1992/06/01 00:00 [pubmed]
PHST- 1992/06/01 00:01 [medline]
PHST- 1992/06/01 00:00 [entrez]
AID - 10.1002/ana.410310618 [doi]
PST - ppublish
SO  - Ann Neurol. 1992 Jun;31(6):675-7. doi: 10.1002/ana.410310618.