PMID- 15153682
OWN - NLM
STAT- MEDLINE
DCOM- 20040720
LR  - 20190607
IS  - 1341-1357 (Print)
IS  - 0007-5124 (Linking)
VI  - 53
IP  - 2
DP  - 2004 Apr
TI  - Differences in responsiveness of mouse strain against p-benzoquinone as assessed 
      by non-radioisotopic murine local lymph node assay.
PG  - 171-3
AB  - The non-radioisotopic modification of murine local lymph node assay (LLNA) by 
      using 5-bromo-2'-deoxyuridine (BrdU) was conducted to investigate the 
      strain-related difference of the responsiveness of mice to p-benzoquinone (PBQ) 
      with BALB/cAnN, CBA/JN and CD-1 mouse strains. Strain and dose related 
      differences were analyzed by two-way analysis of variance (two-way ANOVA). CBA/JN 
      was considered to be the highest responsive strain to PBQ, and interaction was 
      detected between CD-1 and each of the other inbred strains. These results support 
      the recommendation in the OECD test guideline 429 and the skin sensitization test 
      guideline of US-EPA with regard to the selection of mouse strain for LLNA.
FAU - Takeyoshi, Masahiro
AU  - Takeyoshi M
AD  - Hita Laboratory, Chemicals Evaluation and Research Institute, Japan, Oita, Japan.
FAU - Noda, Shuji
AU  - Noda S
FAU - Yamasaki, Kanji
AU  - Yamasaki K
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - Exp Anim
JT  - Experimental animals
JID - 9604830
RN  - 0 (Benzoquinones)
RN  - 3T006GV98U (quinone)
RN  - G34N38R2N1 (Bromodeoxyuridine)
SB  - IM
MH  - Analysis of Variance
MH  - Animals
MH  - Benzoquinones/*toxicity
MH  - Bromodeoxyuridine/metabolism
MH  - Dose-Response Relationship, Drug
MH  - *Local Lymph Node Assay
MH  - Lymph Nodes/*drug effects/metabolism
MH  - Mice
MH  - Mice, Inbred Strains/*metabolism
EDAT- 2004/05/22 05:00
MHDA- 2004/07/21 05:00
CRDT- 2004/05/22 05:00
PHST- 2004/05/22 05:00 [pubmed]
PHST- 2004/07/21 05:00 [medline]
PHST- 2004/05/22 05:00 [entrez]
AID - 10.1538/expanim.53.171 [doi]
PST - ppublish
SO  - Exp Anim. 2004 Apr;53(2):171-3. doi: 10.1538/expanim.53.171.