PMID- 15159058
OWN - NLM
STAT- MEDLINE
DCOM- 20040715
LR  - 20081121
IS  - 0161-5890 (Print)
IS  - 0161-5890 (Linking)
VI  - 41
IP  - 2-3
DP  - 2004 Jun
TI  - Dendritic cells and complement: at the cross road of innate and adaptive 
      immunity.
PG  - 133-40
AB  - The interaction between different components of the immune system plays a pivotal 
      role in the overall development of immune responses. Dendritic cells (DCs) and 
      complement are essential components of innate immunity. They have been shown to 
      be relevant both in the induction of adaptive immune responses and in maintenance 
      of tolerance. However, hyperactivity of these systems has also been demonstrated 
      to be detrimental in various disease states. Despite increased insight into 
      dendritic cell biology, relatively little is known about possible interactions 
      between dendritic cells and complement. This review focuses on novel findings, 
      which have started to shed light on these intriguing components of the innate 
      immune system.
FAU - Castellano, Giuseppe
AU  - Castellano G
AD  - Department of Nephrology, Leiden University Medical Center, C3-P, Albinusdreef 2, 
      P.O. Box 9600, 2333 ZA Leiden, The Netherlands.
FAU - Woltman, Andrea M
AU  - Woltman AM
FAU - Schena, Francesco Paolo
AU  - Schena FP
FAU - Roos, Anja
AU  - Roos A
FAU - Daha, Mohamed R
AU  - Daha MR
FAU - van Kooten, Cees
AU  - van Kooten C
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Mol Immunol
JT  - Molecular immunology
JID - 7905289
RN  - 9007-36-7 (Complement System Proteins)
SB  - IM
MH  - Animals
MH  - Complement System Proteins/*immunology
MH  - Dendritic Cells/*immunology
MH  - Humans
MH  - Immunity, Cellular
MH  - Immunity, Innate
RF  - 86
EDAT- 2004/05/26 05:00
MHDA- 2004/07/16 05:00
CRDT- 2004/05/26 05:00
PHST- 2004/05/26 05:00 [pubmed]
PHST- 2004/07/16 05:00 [medline]
PHST- 2004/05/26 05:00 [entrez]
AID - S0161589004000811 [pii]
AID - 10.1016/j.molimm.2004.03.018 [doi]
PST - ppublish
SO  - Mol Immunol. 2004 Jun;41(2-3):133-40. doi: 10.1016/j.molimm.2004.03.018.