PMID- 15159366
OWN - NLM
STAT- MEDLINE
DCOM- 20040701
LR  - 20220408
IS  - 0820-3946 (Print)
IS  - 1488-2329 (Electronic)
IS  - 0820-3946 (Linking)
VI  - 170
IP  - 11
DP  - 2004 May 25
TI  - The Canadian Adverse Events Study: the incidence of adverse events among hospital 
      patients in Canada.
PG  - 1678-86
AB  - BACKGROUND: Research into adverse events (AEs) has highlighted the need to 
      improve patient safety. AEs are unintended injuries or complications resulting in 
      death, disability or prolonged hospital stay that arise from health care 
      management. We estimated the incidence of AEs among patients in Canadian acute 
      care hospitals. METHODS: We randomly selected 1 teaching, 1 large community and 2 
      small community hospitals in each of 5 provinces (British Columbia, Alberta, 
      Ontario, Quebec and Nova Scotia) and reviewed a random sample of charts for 
      nonpsychiatric, nonobstetric adult patients in each hospital for the fiscal year 
      2000. Trained reviewers screened all eligible charts, and physicians reviewed the 
      positively screened charts to identify AEs and determine their preventability. 
      RESULTS: At least 1 screening criterion was identified in 1527 (40.8%) of 3745 
      charts. The physician reviewers identified AEs in 255 of the charts. After 
      adjustment for the sampling strategy, the AE rate was 7.5 per 100 hospital 
      admissions (95% confidence interval [CI] 5.7- 9.3). Among the patients with AEs, 
      events judged to be preventable occurred in 36.9% (95% CI 32.0%-41.8%) and death 
      in 20.8% (95% CI 7.8%-33.8%). Physician reviewers estimated that 1521 additional 
      hospital days were associated with AEs. Although men and women experienced equal 
      rates of AEs, patients who had AEs were significantly older than those who did 
      not (mean age [and standard deviation] 64.9 [16.7] v. 62.0 [18.4] years; p = 
      0.016). INTERPRETATION: The overall incidence rate of AEs of 7.5% in our study 
      suggests that, of the almost 2.5 million annual hospital admissions in Canada 
      similar to the type studied, about 185 000 are associated with an AE and close to 
      70 000 of these are potentially preventable.
FAU - Baker, G Ross
AU  - Baker GR
AD  - Department of Health Policy, Management and Evaluation, University of Toronto, 
      McMurrich Building Room 2031, 12 Queen's Park Crescent West, Toronto, Ontario M5S 
      1A8, Canada. ross.baker@utoronto.ca
FAU - Norton, Peter G
AU  - Norton PG
FAU - Flintoft, Virginia
AU  - Flintoft V
FAU - Blais, Regis
AU  - Blais R
FAU - Brown, Adalsteinn
AU  - Brown A
FAU - Cox, Jafna
AU  - Cox J
FAU - Etchells, Ed
AU  - Etchells E
FAU - Ghali, William A
AU  - Ghali WA
FAU - Hebert, Philip
AU  - Hebert P
FAU - Majumdar, Sumit R
AU  - Majumdar SR
FAU - O'Beirne, Maeve
AU  - O'Beirne M
FAU - Palacios-Derflingher, Luz
AU  - Palacios-Derflingher L
FAU - Reid, Robert J
AU  - Reid RJ
FAU - Sheps, Sam
AU  - Sheps S
FAU - Tamblyn, Robyn
AU  - Tamblyn R
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Multicenter Study
PT  - Randomized Controlled Trial
PL  - Canada
TA  - CMAJ
JT  - CMAJ : Canadian Medical Association journal = journal de l'Association medicale 
      canadienne
JID - 9711805
SB  - IM
CIN - CMAJ. 2004 May 25;170(11):1688-9. PMID: 15159368
CIN - CMAJ. 2004 Oct 12;171(8):829, 832; author reply 834. PMID: 15477606
CIN - CMAJ. 2004 Oct 12;171(8):832; author reply 834. PMID: 15477609
CIN - CMAJ. 2004 Oct 12;171(8):833-4; author reply 834. PMID: 15477610
CIN - CMAJ. 2004 Oct 12;171(8):833; author reply 834. PMID: 15477611
CIN - CMAJ. 2004 Oct 12;171(8):834; author reply 834. PMID: 15477613
CIN - CMAJ. 2010 Aug 10;182(11):1214. PMID: 20696812
MH  - Canada/epidemiology
MH  - Health Facility Size
MH  - Hospital Mortality
MH  - Hospitals, Community/*standards/statistics & numerical data
MH  - Hospitals, Teaching/*standards/statistics & numerical data
MH  - Humans
MH  - Iatrogenic Disease/*epidemiology/prevention & control
MH  - Incidence
MH  - Length of Stay/statistics & numerical data
MH  - Medical Audit/*methods
MH  - Medical Errors/prevention & control/*statistics & numerical data
MH  - Patient Admission/statistics & numerical data
MH  - Patient Advocacy
MH  - Safety Management/*standards
PMC - PMC408508
EDAT- 2004/05/26 05:00
MHDA- 2004/07/02 05:00
PMCR- 2004/05/25
CRDT- 2004/05/26 05:00
PHST- 2004/05/26 05:00 [pubmed]
PHST- 2004/07/02 05:00 [medline]
PHST- 2004/05/26 05:00 [entrez]
PHST- 2004/05/25 00:00 [pmc-release]
AID - 0002792-200405250-00028 [pii]
AID - 10.1503/cmaj.1040498 [doi]
PST - ppublish
SO  - CMAJ. 2004 May 25;170(11):1678-86. doi: 10.1503/cmaj.1040498.