PMID- 15167690 OWN - NLM STAT- MEDLINE DCOM- 20050324 LR - 20191108 IS - 0955-8829 (Print) IS - 0955-8829 (Linking) VI - 14 IP - 2 DP - 2004 Jun TI - Monocyte chemoattractant protein-1 promoter -2518 polymorphism and schizophrenia in the Korean population. PG - 65-7 AB - The purpose of the present study was to investigate the association between the monocyte chemoattractant protein-1 (MCP-1) promoter -2518 polymorphism and schizophrenia. One hundred and twenty-three schizophrenic inpatients and 114 healthy controls participated in this study. Genotyping was performed by polymerase chain reaction-restriction fragment length polymorphism. Genotype and allele distributions in patients with schizophrenia were not significantly different from those of the controls. However, distributions of genotypes and alleles were marginally different when considering subjects with positive and negative symptomatology. The present study therefore calls for further studies on the potential role of the MCP-1 promoter -2518 polymorphism in clinical heterogeneity of schizophrenia. FAU - Pae, Chi-Un AU - Pae CU AD - Department of Psychiatry, Kangnam St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seocho-Gu, Seoul, Korea. FAU - Chung, Kyoo-In AU - Chung KI FAU - Kim, Jung-Jin AU - Kim JJ FAU - Yu, Hye-Sook AU - Yu HS FAU - Lee, Chang-Uk AU - Lee CU FAU - Lee, Soo-Jung AU - Lee SJ FAU - Lee, Chul AU - Lee C FAU - Jun, Tae-Youn AU - Jun TY FAU - Serretti, Alessandro AU - Serretti A FAU - Paik, In-Ho AU - Paik IH LA - eng PT - Comparative Study PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Psychiatr Genet JT - Psychiatric genetics JID - 9106748 RN - 0 (CCL2 protein, human) RN - 0 (Chemokine CCL2) RN - 0 (DNA Primers) RN - 9007-49-2 (DNA) SB - IM MH - Base Sequence MH - Chemokine CCL2/*genetics MH - DNA/blood/genetics/isolation & purification MH - DNA Primers MH - Humans MH - Korea MH - Promoter Regions, Genetic/*genetics MH - Reference Values MH - Schizophrenia/*genetics MH - Sequence Deletion EDAT- 2004/05/29 05:00 MHDA- 2005/03/25 09:00 CRDT- 2004/05/29 05:00 PHST- 2004/05/29 05:00 [pubmed] PHST- 2005/03/25 09:00 [medline] PHST- 2004/05/29 05:00 [entrez] AID - 00041444-200406000-00002 [pii] AID - 10.1097/01.ypg.0000128764.07344.06 [doi] PST - ppublish SO - Psychiatr Genet. 2004 Jun;14(2):65-7. doi: 10.1097/01.ypg.0000128764.07344.06.