PMID- 15182651
OWN - NLM
STAT- MEDLINE
DCOM- 20040817
LR  - 20061115
IS  - 1007-8738 (Print)
IS  - 1007-8738 (Linking)
VI  - 19
IP  - 6
DP  - 2003 Nov
TI  - [Significance of detecting urinary monocyte chemotactic peptide-1 in renal 
      transplant recipient].
PG  - 563-4
AB  - AIM: To detect the content of monocyte chemotactic peptide-1(MCP-1) and to 
      investigate the role of MCP-1 in acute renal graft rejection. METHODS: Urinary 
      MCP-1 level was detected by avidin biotin complex(ABC)ELISA. RESULTS: Urinary 
      MCP-1 levels in renal function stable renal transplantation of recipients and 
      control group were (416+/-21) microg/L and (408+/-11) microg/L, respectively. 
      Urinary MCP-1 level in renal transplantation recipients with acute rejection was 
      (1195+/-58) microg/L, which was notably higher than that in control group and 
      renal function stable recipients (P<0.01). After anti-rejection treatment, 
      urinary MCP-1 level decreased markedly in patients who responded to treatment. 
      CONCLUSION: The urinary MCP-1 level is correlated closely with acute renal graft 
      rejection and its increase may indicate ongoing acute renal rejection. Detection 
      of urinary MCP-1 level may contribute to early diagnosis and prognostic judgement 
      of acute graft rejection.
FAU - Sun, Xing-hui
AU  - Sun XH
AD  - Department of Urology, Fuzhou General Hospital of Nanjing Military Area, Fuzhou 
      350025, China.
FAU - Tan, Jian-ming
AU  - Tan JM
FAU - Wu, Wei-zhen
AU  - Wu WZ
FAU - Lin, Wen-hong
AU  - Lin WH
FAU - Li, Qian-sheng
AU  - Li QS
FAU - Fang, Yu-hua
AU  - Fang YH
LA  - chi
PT  - English Abstract
PT  - Journal Article
PL  - China
TA  - Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi
JT  - Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular 
      immunology
JID - 101139110
RN  - 0 (Chemokine CCL2)
SB  - IM
MH  - Acute Disease
MH  - Adult
MH  - Chemokine CCL2/physiology/*urine
MH  - Female
MH  - Graft Rejection/*etiology
MH  - Humans
MH  - Kidney Transplantation/*immunology
MH  - Male
MH  - Middle Aged
EDAT- 2004/06/09 05:00
MHDA- 2004/08/18 05:00
CRDT- 2004/06/09 05:00
PHST- 2004/06/09 05:00 [pubmed]
PHST- 2004/08/18 05:00 [medline]
PHST- 2004/06/09 05:00 [entrez]
PST - ppublish
SO  - Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2003 Nov;19(6):563-4.