PMID- 15192764
OWN - NLM
STAT- MEDLINE
DCOM- 20050203
LR  - 20200413
IS  - 0021-7557 (Print)
IS  - 0021-7557 (Linking)
VI  - 80
IP  - 3
DP  - 2004 May-Jun
TI  - [The impact of malnutrition on idiopathic dilated cardiomyopathy in children].
PG  - 211-6
AB  - OBJECTIVE: To analyze the prognostic value of malnutrition in children with 
      idiopathic dilated cardiomyopathy. METHODS: This is a retrospective study of 165 
      patients with idiopathic dilated cardiomyopathy, diagnosed from September 1979 to 
      March 2003. It analyzed the following variables: gender, age, previous viral 
      illness in the preceding 3 months, functional class according to the New York 
      Heart Association (NYHA), evaluation of nutritional status (normal vs. 
      malnutrition), percentile and standard deviation (z index) of weight. Weight was 
      measured 744 times during the first 72 months, 93 during the first month. 
      Statistical analysis was performed by Chi Squared, Student t test and analysis of 
      variance for repeated measures (ANOVA). Ninety-five percent confidence intervals 
      (CI95) and odds ratios (OR) were calculated. An alpha value of 0.05 and beta of 
      0.80 were used. RESULTS: Mean age at presentation was 2.2+/-3.2 years with higher 
      incidence in those younger than 2 years (75.8%-CI95 = 68.5% to 82.1%) (p < 
      0.0001). NYHA classes III and IV were observed in 81.2% (CI95 = 74.4% to 86.9%) 
      (p < 0.0001) and all 40 deaths were this group (p = 0.0008). At presentation, 
      myocarditis occurred in 39.4% (CI95 = 31.9% to 47.3%) (p = 0.0001) and a high 
      level of association between myocarditis and previous viral illness was observed 
      (p = 0.0005) (OR = 3.15-CI95 = 1.55 to 6.44). Malnutrition at presentation did 
      not influence death (p = 0.10), however progressive malnutrition was a marker for 
      death (p = 0.02) (OR = 3.21-CI95 = 1.04 to 9.95). No significant differences 
      weight percentiles (p = 0.15) or in z scores (p = 0.14) were observed. Observed 
      mean weight percentiles (34.9+/-32.6 vs. 8.6+/-16.0) (p < 0.0001) and z scores 
      (-0.62+/-1.43 vs. -2.02+/-1.12) (p < 0.0001) during the study period were greater 
      among survivors. ANOVA demonstrated significant differences in weight percentile 
      progression (p = 0.0417) and z scores (p = 0.0005) from the first month onwards. 
      CONCLUSION: The evaluation of nutritional status is easy to perform, it does not 
      imply additional costs and should become routine for children with chronic heart 
      failure.
FAU - Azevedo, Vitor M P
AU  - Azevedo VM
AD  - Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil. 
      vitoraze@cardiol.br
FAU - Albanesi Filho, Francisco M
AU  - Albanesi Filho FM
FAU - Santos, Marco A
AU  - Santos MA
FAU - Castier, Marcia B
AU  - Castier MB
FAU - Tura, Bernardo R
AU  - Tura BR
LA  - por
PT  - English Abstract
PT  - Journal Article
TT  - O impacto da desnutricao na cardiomiopatia dilatada idiopatica na infancia.
PL  - Brazil
TA  - J Pediatr (Rio J)
JT  - Jornal de pediatria
JID - 2985188R
SB  - IM
CIN - J Pediatr (Rio J). 2005 Sep-Oct;81(5):355-6. PMID: 16247533
MH  - Age Factors
MH  - Body Weight
MH  - Brazil/epidemiology
MH  - Cardiomyopathy, Dilated/etiology/*mortality
MH  - Child
MH  - Child Nutrition Disorders/*complications
MH  - Child, Preschool
MH  - Epidemiologic Methods
MH  - Female
MH  - Humans
MH  - Infant
MH  - Infant Nutrition Disorders/*complications
MH  - Male
MH  - Nutrition Assessment
MH  - Nutritional Status
MH  - Sex Factors
EDAT- 2004/06/12 05:00
MHDA- 2005/02/04 09:00
CRDT- 2004/06/12 05:00
PHST- 2004/06/12 05:00 [pubmed]
PHST- 2005/02/04 09:00 [medline]
PHST- 2004/06/12 05:00 [entrez]
PST - ppublish
SO  - J Pediatr (Rio J). 2004 May-Jun;80(3):211-6.