PMID- 15196908
OWN - NLM
STAT- MEDLINE
DCOM- 20041019
LR  - 20210119
IS  - 0034-5288 (Print)
IS  - 1532-2661 (Electronic)
IS  - 0034-5288 (Linking)
VI  - 77
IP  - 2
DP  - 2004 Oct
TI  - The presence of co-infections in pigs with clinical signs of PMWS in The 
      Netherlands: a case-control study.
PG  - 177-84
AB  - In this study, 60 pigs with clinical signs of post-weaning multisystemic wasting 
      syndrome (PMWS) from 20 different pig herds and 180 control pigs (without 
      clinical signs of PMWS) were examined to get more insights into the frequencies 
      of porcine circovirus 2 infections and the presence of co-infections in pigs with 
      and without clinical signs of PMWS in the Netherlands. Porcine circovirus type 2 
      was detected in 100% of the pigs with clinical signs of PMWS by virus isolation 
      and/or PCR and in 50% of the pigs from PMWS-free herds. There was an association 
      between the levels of infectious PCV2 and/or PCV2 DNA load and the severity of 
      clinical signs as described for PMWS. A high variation in PCV2 antibody titres 
      was found in the clinically affected pigs, and 27% of these pigs did not mount 
      PCV2 antibody titres higher than 1:200. A concurrent infection of PCV2 and 
      porcine reproductive and respiratory syndrome virus (PRRSV) was found in at least 
      83% of the pigs with clinical signs of PMWS and in 35% of the pigs from PMWS-free 
      herds. Co-infections of European- and American-type PRRSV were detected only in 
      PMWS herds and in one control herd with a history of PMWS clinical signs.
FAU - Wellenberg, G J
AU  - Wellenberg GJ
AD  - Division of Infectious Diseases, Animal Sciences Group (ID-Lelystad), Edelhertweg 
      15, P.O. Box 65, 8200 AB, Lelystad, The Netherlands. gerard.wellenberg@wur.nl
FAU - Stockhofe-Zurwieden, N
AU  - Stockhofe-Zurwieden N
FAU - Boersma, W J A
AU  - Boersma WJ
FAU - De Jong, M F
AU  - De Jong MF
FAU - Elbers, A R W
AU  - Elbers AR
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Res Vet Sci
JT  - Research in veterinary science
JID - 0401300
RN  - 0 (Antibodies, Viral)
RN  - 0 (DNA, Viral)
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/analysis
MH  - Case-Control Studies
MH  - Circoviridae Infections/*veterinary/virology
MH  - Circovirus/genetics/*isolation & purification
MH  - DNA, Viral/analysis
MH  - Enzyme-Linked Immunosorbent Assay/veterinary
MH  - Immunoenzyme Techniques/veterinary
MH  - Kidney/virology
MH  - Lung/virology
MH  - Lymph Nodes/virology
MH  - Netherlands/epidemiology
MH  - Porcine Reproductive and Respiratory Syndrome/*virology
MH  - Porcine respiratory and reproductive syndrome virus/genetics/*isolation & 
      purification
MH  - RNA, Viral/isolation & purification
MH  - Reverse Transcriptase Polymerase Chain Reaction/veterinary
MH  - Spleen/virology
MH  - Swine
MH  - Swine Diseases/*virology
MH  - Wasting Syndrome/*veterinary/virology
PMC - PMC7125932
EDAT- 2004/06/16 05:00
MHDA- 2004/10/20 09:00
PMCR- 2004/05/10
CRDT- 2004/06/16 05:00
PHST- 2004/03/18 00:00 [accepted]
PHST- 2004/06/16 05:00 [pubmed]
PHST- 2004/10/20 09:00 [medline]
PHST- 2004/06/16 05:00 [entrez]
PHST- 2004/05/10 00:00 [pmc-release]
AID - S0034528804000608 [pii]
AID - 10.1016/j.rvsc.2004.03.007 [doi]
PST - ppublish
SO  - Res Vet Sci. 2004 Oct;77(2):177-84. doi: 10.1016/j.rvsc.2004.03.007.