PMID- 15199446
OWN - NLM
STAT- MEDLINE
DCOM- 20040729
LR  - 20051116
IS  - 1528-9648 (Print)
IS  - 1528-9648 (Linking)
VI  - 3
IP  - 4
DP  - 2003 Nov
TI  - Low-molecular-weight heparins for the treatment of acute coronary syndromes.
PG  - 391-402
AB  - Low-molecular-weight heparins (LMWHs) possess several advantages over 
      unfractionated heparin (UFH) for the treatment of acute coronary syndromes 
      (ACSs). Already a class I indication for the treatment of unstable angina/non-ST 
      elevation myocardial infarction (UA/NSTEMI), LMWHs also show promise in the 
      setting of ST elevation myocardial infarction (STEMI) and percutaneous coronary 
      intervention (PCI). Moreover, a growing body of evidence has demonstrated 
      equivalent safety of LMWH with concomitant use of glycoprotein IIb/IIIa 
      inhibitors. Larger clinical studies are needed to confirm the safety and efficacy 
      of LMWH as an antithrombin for the treatment across the spectrum of ACS.
FAU - Wong, Graham C
AU  - Wong GC
AD  - Vancouver General Hospital, University of British Columbia, Vancouver, BC, 
      Canada.
FAU - Giugliano, Robert P
AU  - Giugliano RP
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Semin Vasc Med
JT  - Seminars in vascular medicine
JID - 100940307
RN  - 0 (Fibrinolytic Agents)
RN  - 0 (Heparin, Low-Molecular-Weight)
RN  - 0 (Platelet Glycoprotein GPIIb-IIIa Complex)
SB  - IM
MH  - Angina, Unstable/*drug therapy/physiopathology
MH  - Drug Therapy, Combination
MH  - Fibrinolytic Agents/pharmacology/*therapeutic use
MH  - Heparin, Low-Molecular-Weight/pharmacology/*therapeutic use
MH  - Humans
MH  - Myocardial Infarction/*drug therapy/physiopathology
MH  - Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors
RF  - 57
EDAT- 2004/06/17 05:00
MHDA- 2004/07/30 05:00
CRDT- 2004/06/17 05:00
PHST- 2004/06/17 05:00 [pubmed]
PHST- 2004/07/30 05:00 [medline]
PHST- 2004/06/17 05:00 [entrez]
AID - 10.1055/s-2004-817703 [doi]
PST - ppublish
SO  - Semin Vasc Med. 2003 Nov;3(4):391-402. doi: 10.1055/s-2004-817703.