PMID- 15205713
OWN - NLM
STAT- MEDLINE
DCOM- 20040820
LR  - 20181113
IS  - 0937-941X (Print)
IS  - 0937-941X (Linking)
VI  - 15
IP  - 6
DP  - 2004 Jun
TI  - Hormone therapy and risk of non-vertebral fracture: Geelong osteoporosis study.
PG  - 434-8
AB  - In this population-based study, we evaluated the association between exposure to 
      hormone therapy (HT), bone mineral density (BMD) and the prevalence of 
      non-vertebral fractures. The study was set in a region located in southeastern 
      Australia where complete fracture ascertainment was determined from radiological 
      reports. Current HT use for at least 6 months was ascertained in women with 
      non-vertebral fractures [median age 70.9 years; inter-quartile range (IQR) 
      66.5-75.9 years] and randomly selected controls (median age 70.8 years; IQR 
      65.2-75.0 years). Current HT use was documented in 20 of 262 cases and 49 of 364 
      controls. The odds ratio (OR) for non-vertebral fracture associated with HT use 
      was 0.53 (95% CI 0.31-0.92). HT use was associated with 2.6-7.5% higher BMD at 
      axial and appendicular sites. HT use is associated with a halving of risk for 
      non-vertebral fractures and higher BMD.
FAU - Pasco, Julie A
AU  - Pasco JA
AD  - Department of Clinical and Biomedical Sciences: Barwon Health, The University of 
      Melbourne, P.O. Box 281, 3220 Geelong, Australia. juliep@barwonhealth.org.au
FAU - Kotowicz, Mark A
AU  - Kotowicz MA
FAU - Henry, Margaret J
AU  - Henry MJ
FAU - Sanders, Kerrie M
AU  - Sanders KM
FAU - Seeman, Ego
AU  - Seeman E
FAU - Nicholson, Geoffrey C
AU  - Nicholson GC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20040214
PL  - England
TA  - Osteoporos Int
JT  - Osteoporosis international : a journal established as result of cooperation 
      between the European Foundation for Osteoporosis and the National Osteoporosis 
      Foundation of the USA
JID - 9100105
SB  - IM
MH  - Aged
MH  - Bone Density
MH  - Case-Control Studies
MH  - *Estrogen Replacement Therapy
MH  - Female
MH  - Fractures, Bone/epidemiology/*prevention & control
MH  - Humans
MH  - Middle Aged
MH  - Odds Ratio
MH  - Prevalence
MH  - Risk Assessment
EDAT- 2004/06/19 05:00
MHDA- 2004/08/21 05:00
CRDT- 2004/06/19 05:00
PHST- 2003/04/25 00:00 [received]
PHST- 2003/12/08 00:00 [accepted]
PHST- 2004/06/19 05:00 [pubmed]
PHST- 2004/08/21 05:00 [medline]
PHST- 2004/06/19 05:00 [entrez]
AID - 10.1007/s00198-003-1574-1 [doi]
PST - ppublish
SO  - Osteoporos Int. 2004 Jun;15(6):434-8. doi: 10.1007/s00198-003-1574-1. Epub 2004 
      Feb 14.