PMID- 15212142
OWN - NLM
STAT- MEDLINE
DCOM- 20041216
LR  - 20190727
IS  - 0040-8727 (Print)
IS  - 0040-8727 (Linking)
VI  - 203
IP  - 2
DP  - 2004 Jun
TI  - Differential localization of brain-type and epidermal-type fatty acid binding 
      proteins in the adrenal gland of mice.
PG  - 77-86
AB  - In immuno-light and -electron microscopy, brain-type fatty acid binding protein 
      (B-FABP) is localized in the sustentacular cells enclosing the chromaffin cells 
      in the adrenal medulla. This represents another new feature commonly shared by 
      the sustentacular cells and ganglionic satellite cells, the latter of which has 
      already been reported to localize this molecule, and suggests a common feature in 
      lipid metabolism shared by the two cells enclosing peripheral neurons and 
      paraneurons. On the other hand, epidermal-type fatty acid binding protein 
      (E-FABP) is localized in two discrete cells in the adrenal gland: the one is a 
      subpopulation of intra-adrenal macrophages which are intensely immunoreactive for 
      F4/80, a marker of macrophages, and are rich in pleomorphic lysosomes. Because of 
      their direct apposition to adjacent cortical endocrine cells and medullary 
      chromaffin cells, the macrophages may be involved not only in phagocytosis of 
      degenerating adrenal cells but also in exertion of some yet unknown effects on 
      the endocrine function of the cortical and medullary cells via humoral factors 
      such as cytokines which have recently been known to be secreted by macrophages. 
      The other is a population of cells having scanty perikaryal cytoplasm poor in 
      organneles and several thinny extended processes in the cortex and exhibiting 
      weak immunoreactivity for E-FABP. The possible natures of these cells 
      immunoreactive for E-FABP are discussed in view of a subpopulation of endothelial 
      cells or the dendritic cells of antigen-presenting property.
FAU - Yun, Xia
AU  - Yun X
AD  - Division of Histology, Department of Cell Biology, Graduate School of Medicine, 
      Tohoku University, Sendai 980-8575, Japan.
FAU - Nourani, Mohammad Reza
AU  - Nourani MR
FAU - Abdelwahab, Soha Abdelkawi
AU  - Abdelwahab SA
FAU - Kitanaka, Noriko
AU  - Kitanaka N
FAU - Owada, Yuji
AU  - Owada Y
FAU - Spener, Friedrich
AU  - Spener F
FAU - Iwasa, Hiroo
AU  - Iwasa H
FAU - Takahashi, Akira
AU  - Takahashi A
FAU - Kondo, Hisatake
AU  - Kondo H
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Tohoku J Exp Med
JT  - The Tohoku journal of experimental medicine
JID - 0417355
RN  - 0 (Carrier Proteins)
RN  - 0 (Fabp5 protein, mouse)
RN  - 0 (Fabp7 protein, mouse)
RN  - 0 (Fatty Acid-Binding Protein 7)
RN  - 0 (Fatty Acid-Binding Proteins)
RN  - 0 (Neoplasm Proteins)
RN  - 0 (Nerve Tissue Proteins)
SB  - IM
MH  - Adrenal Cortex/metabolism
MH  - Adrenal Glands/*metabolism
MH  - Animals
MH  - Carrier Proteins/*biosynthesis
MH  - Cell Membrane/metabolism
MH  - Chromaffin Cells/cytology/metabolism
MH  - Cytoplasm/metabolism
MH  - Dendritic Cells/cytology
MH  - Endothelium/cytology
MH  - Fatty Acid-Binding Protein 7
MH  - Fatty Acid-Binding Proteins
MH  - Kidney Medulla/metabolism
MH  - Lipid Metabolism
MH  - Macrophages/metabolism
MH  - Male
MH  - Mice
MH  - Mice, Inbred C57BL
MH  - Microscopy, Electron, Transmission
MH  - Neoplasm Proteins/*biosynthesis
MH  - Nerve Tissue Proteins/*biosynthesis
MH  - Neurons/metabolism
MH  - Phenotype
EDAT- 2004/06/24 05:00
MHDA- 2004/12/17 09:00
CRDT- 2004/06/24 05:00
PHST- 2004/06/24 05:00 [pubmed]
PHST- 2004/12/17 09:00 [medline]
PHST- 2004/06/24 05:00 [entrez]
AID - 10.1620/tjem.203.77 [doi]
PST - ppublish
SO  - Tohoku J Exp Med. 2004 Jun;203(2):77-86. doi: 10.1620/tjem.203.77.