PMID- 15215374 OWN - NLM STAT- MEDLINE DCOM- 20040820 LR - 20181113 IS - 1362-4962 (Electronic) IS - 0305-1048 (Print) IS - 0305-1048 (Linking) VI - 32 IP - Web Server issue DP - 2004 Jul 1 TI - The sequencing-based typing tool of dbMHC: typing highly polymorphic gene sequences. PG - W173-5 AB - The dbMHC resource (http://www.ncbi.nlm.nih.gov/mhc/sbt.cgi?cmd=main) at the National Center for Biotechnology Information (NCBI) has developed an online tool for evaluating the allelic composition of sequencing-based typing (SBT) results of cDNA or genomic sequences. Whether the samples are heterozygous, haploid or a combination of the two, they can be compared with two up-to-date databases of all known alleles of several human leukocyte antigen (HLA) and killer cell immunoglobulin-like receptor (KIR) loci. The results of the submission are returned as a table of potential allele hits, along with the respective base changes and an interactive sequence viewer for close examination of the alignment. FAU - Helmberg, Wolfgang AU - Helmberg W AD - National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 45, 8600 Rockville Pike, Bethesda, MD 20894, USA. helmberg@ncbi.nlm.nih.gov FAU - Dunivin, Raymond AU - Dunivin R FAU - Feolo, Michael AU - Feolo M LA - eng PT - Journal Article PL - England TA - Nucleic Acids Res JT - Nucleic acids research JID - 0411011 RN - 0 (HLA Antigens) RN - 0 (Receptors, Immunologic) RN - 0 (Receptors, KIR) SB - IM MH - Algorithms MH - Alleles MH - DNA Fingerprinting MH - Databases, Nucleic Acid MH - HLA Antigens/*genetics MH - Internet MH - *Polymorphism, Genetic MH - Receptors, Immunologic/*genetics MH - Receptors, KIR MH - Sequence Alignment MH - Sequence Analysis, DNA MH - *Software PMC - PMC441562 EDAT- 2004/06/25 05:00 MHDA- 2004/08/21 05:00 PMCR- 2004/07/01 CRDT- 2004/06/25 05:00 PHST- 2004/06/25 05:00 [pubmed] PHST- 2004/08/21 05:00 [medline] PHST- 2004/06/25 05:00 [entrez] PHST- 2004/07/01 00:00 [pmc-release] AID - 32/suppl_2/W173 [pii] AID - gkh424 [pii] AID - 10.1093/nar/gkh424 [doi] PST - ppublish SO - Nucleic Acids Res. 2004 Jul 1;32(Web Server issue):W173-5. doi: 10.1093/nar/gkh424.