PMID- 15217741
OWN - NLM
STAT- MEDLINE
DCOM- 20041213
LR  - 20220410
IS  - 1157-5999 (Print)
IS  - 1157-5999 (Linking)
VI  - 14
IP  - 1
DP  - 2004 Jan-Mar
TI  - [Effect of iron supplementation among pregnant women at mother-and-baby clinic of 
      Sidi Bel Abbes, West Algeria].
PG  - 21-9
AB  - Iron deficiency is the most prevalent nutritional disorder worldwide, especially 
      in developing countries. It occurs when iron absorption does not equal iron 
      requirements plus iron loss. Because iron requirements are especially high in 
      pregnant women, infants, young children, and adolescents, these groups run a high 
      risk of iron-deficiency anemia. In this controlled prospective and longitudinal 
      study of 83 pregnant women, we explored the correlations between various 
      epidemiological characteristics and the onset of anemia. We also looked at the 
      effect of iron supplementation on the hematological parameters among pregnant 
      women with anemia. Blood counts during the first trimester of pregnancy (3 months 
      +/- 2 weeks' gestation) revealed that 31 of the 83 subjects (37.3%) women had 
      anemia (Hb < 11 g/100 ml): 16 moderate (7 g/dl < or = Hb < 10 g/dl) and 15 mild 
      (10 g/dl < or = Hb < 11 g/dl). We detected no cases of severe anemia in our 
      study. Nor did we find a clear correlation between anemia and such factors as age 
      (r = 0.09), number of pregnancies (r = - 0.30), interval between pregnancies (r = 
      0.03), or number of abortions (r = - 0.18). Nonetheless, iron supplementation of 
      30 mg/day, prescribed for four months for all the women with anemia (n = 31), 
      improved some of these hematological parameters, increasing hemoglobin and serum 
      iron levels in particular. These two parameters were strongly positively 
      correlated (r = 0.89). We also noted that the red blood cell count (RBC) and the 
      mean corpuscular hemoglobin concentration (MCHC) both increased significantly (p 
      < 0.05) among the anemic women receiving iron supplements. The prevalence of 
      anemia fell from 34.1% in the first trimester, before supplementation, to 6.3% in 
      the third trimester. This finding suggests that the supplementation prevented the 
      fall in hemoglobin and serum iron that occurred among the women without anemia. 
      We think that iron supplementation is a good strategy for treating and preventing 
      anemia during pregnancy.
FAU - Moulessehoul, Soraya
AU  - Moulessehoul S
AD  - Laboratoire de biotoxicologie, Departement de biologie, Faculte des sciences, 
      Universite Djillali Liabes, BP 89, Faubourg Larbi Ben M'hidi, 22000 Sidi Bel 
      Abbes, Algeria. s.moulessehoul@univ-sba.dz
FAU - Demmouche, Abbassia
AU  - Demmouche A
FAU - Chafi, Yazid
AU  - Chafi Y
FAU - Benali, Mohamed
AU  - Benali M
LA  - fre
PT  - English Abstract
PT  - Journal Article
TT  - Impact de la supplementation en fer chez des femmes enceintes suivies au centre 
      de Protection maternelle et infantile de Sidi Bel Abbes (Ouest algerien).
PL  - France
TA  - Sante
JT  - Sante (Montrouge, France)
JID - 9212437
RN  - E1UOL152H7 (Iron)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Algeria
MH  - Anemia, Iron-Deficiency/blood/*drug therapy/epidemiology
MH  - *Dietary Supplements
MH  - Female
MH  - Humans
MH  - Iron/*administration & dosage/blood
MH  - Longitudinal Studies
MH  - Maternal-Child Health Centers
MH  - Pregnancy
MH  - Pregnancy Complications, Hematologic/blood/*drug therapy/epidemiology
MH  - Prospective Studies
EDAT- 2004/06/26 05:00
MHDA- 2004/12/16 09:00
CRDT- 2004/06/26 05:00
PHST- 2004/06/26 05:00 [pubmed]
PHST- 2004/12/16 09:00 [medline]
PHST- 2004/06/26 05:00 [entrez]
PST - ppublish
SO  - Sante. 2004 Jan-Mar;14(1):21-9.