PMID- 15229797
OWN - NLM
STAT- MEDLINE
DCOM- 20040819
LR  - 20091119
IS  - 0271-8235 (Print)
IS  - 0271-8235 (Linking)
VI  - 24
IP  - 1
DP  - 2004 Mar
TI  - Autoimmune myasthenia gravis in childhood.
PG  - 101-10
AB  - The recent identification of an autoimmune process targeting muscle-specific 
      kinase (MuSK) in a subset of seronegative patients with autoimmune myasthenia 
      gravis promises to improve diagnostic accuracy and redirect therapy in at least 
      some seronegative children and adolescents with myasthenia. Clinical features, 
      diagnostic methods, and management strategies pertinent to children with 
      autoimmune myasthenia are discussed, as well as the emerging data regarding the 
      anti-MuSK autoimmune process in myasthenia gravis.
FAU - Andrews, P Ian
AU  - Andrews PI
AD  - University of New South Wales, Australia.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Semin Neurol
JT  - Seminars in neurology
JID - 8111343
RN  - 0 (Adjuvants, Immunologic)
RN  - 0 (Autoantibodies)
RN  - 0 (Cholinesterase Inhibitors)
RN  - 0 (Receptors, Cholinergic)
RN  - EC 2.7.10.1 (MUSK protein, human)
RN  - EC 2.7.10.1 (Receptor Protein-Tyrosine Kinases)
SB  - IM
MH  - Adjuvants, Immunologic/therapeutic use
MH  - Age Factors
MH  - Autoantibodies/immunology
MH  - Child
MH  - Cholinesterase Inhibitors/therapeutic use
MH  - Humans
MH  - Muscle, Skeletal/*immunology/physiopathology
MH  - Myasthenia Gravis/*enzymology/*immunology/physiopathology
MH  - Neuromuscular Junction/enzymology/immunology/physiopathology
MH  - Receptor Protein-Tyrosine Kinases/*immunology
MH  - Receptors, Cholinergic/*immunology
RF  - 92
EDAT- 2004/07/02 05:00
MHDA- 2004/08/20 05:00
CRDT- 2004/07/02 05:00
PHST- 2004/07/02 05:00 [pubmed]
PHST- 2004/08/20 05:00 [medline]
PHST- 2004/07/02 05:00 [entrez]
AID - 10.1055/s-2004-829591 [doi]
PST - ppublish
SO  - Semin Neurol. 2004 Mar;24(1):101-10. doi: 10.1055/s-2004-829591.