PMID- 15239811
OWN - NLM
STAT- MEDLINE
DCOM- 20041028
LR  - 20061115
IS  - 0340-2096 (Print)
IS  - 0340-2096 (Linking)
VI  - 33
IP  - 4
DP  - 2004 Aug
TI  - Histochemical study on neurodegeneration in the olfactory bulb after transient 
      forebrain ischaemia in the Mongolian gerbil.
PG  - 208-11
AB  - In the present study, we investigated the ischaemia-related neurodegeneration in 
      the main and accessory olfactory bulb (AOB) after 5 min transient forebrain 
      ischaemia in the Mongolian gerbil using the acid fuchsin staining method. Between 
      5 and 15 days after ischaemia, acid fuchsin positive cells markedly increased in 
      the external plexiform layer (EPL), mitral cell layer (ML) and glomerular layer 
      (GL) of the main olfactory bulb (MOB), and in the mixed cell layer (MCL) and GL 
      of the AOB. By 30 days after ischaemia reperfusion, acid fuchsin positive neurons 
      were shrunken and showed low acidophilia in somata. Many necrotic vacuoles were 
      found in the EPL and GL of the MOB 30 days after ischaemia. At this time, 
      necrotic vacuoles were very few in the AOB. Therefore, our results suggest that 
      the GL and EPL of the MOB are vulnerable to ischaemic damage at a later time 
      after ischaemic insult, and that the AOB is more resistant to ischaemic damage as 
      compared with the MOB.
FAU - Koh, U S
AU  - Koh US
AD  - Department of Anatomy, College of Medicine, Hallym University, Chunchon 200-702, 
      South Korea.
FAU - Hwang, I K
AU  - Hwang IK
FAU - Lee, J C
AU  - Lee JC
FAU - Lee, H Y
AU  - Lee HY
FAU - Seong, N S
AU  - Seong NS
FAU - Chung, H G
AU  - Chung HG
FAU - Kim, J H
AU  - Kim JH
FAU - Lee, H J
AU  - Lee HJ
FAU - Choi, G P
AU  - Choi GP
FAU - Kang, T-C
AU  - Kang TC
FAU - Won, M H
AU  - Won MH
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Anat Histol Embryol
JT  - Anatomia, histologia, embryologia
JID - 7704218
SB  - IM
MH  - Animals
MH  - *Gerbillinae
MH  - Immunohistochemistry/veterinary
MH  - Ischemic Attack, Transient/complications/pathology/*veterinary
MH  - Male
MH  - Neurodegenerative Diseases/etiology/pathology/*veterinary
MH  - Olfactory Bulb/anatomy & histology/*pathology
MH  - Prosencephalon/blood supply/pathology
MH  - Rodent Diseases/*pathology
EDAT- 2004/07/09 05:00
MHDA- 2004/10/29 09:00
CRDT- 2004/07/09 05:00
PHST- 2004/07/09 05:00 [pubmed]
PHST- 2004/10/29 09:00 [medline]
PHST- 2004/07/09 05:00 [entrez]
AID - AHE538 [pii]
AID - 10.1111/j.1439-0264.2004.00538.x [doi]
PST - ppublish
SO  - Anat Histol Embryol. 2004 Aug;33(4):208-11. doi: 
      10.1111/j.1439-0264.2004.00538.x.