PMID- 15269978 OWN - NLM STAT- MEDLINE DCOM- 20041021 LR - 20211105 IS - 1008-9292 (Print) IS - 1008-9292 (Linking) VI - 33 IP - 4 DP - 2004 Jul TI - [Expressions of bFGF, ET-1 and SCF in dermal papilla cells and the relation to their biological properties]. PG - 296-9 AB - OBJECTIVE: To investigate the expression of bFGF, ET-1 and SCF in different passages of cultured dermal papilla cells (DPC), and their possible effect on biological behaviour of DPC. METHODS: The expression of bFGF, ET-1 and SCF in different passages of cultured DPC was detected by immunocytochemistry and in situ hybridization. RESULT: The expression of ET-1 and SCF in early passages of cultured DPC was stronger, but became negative in late passages (>6 passages). The stronger the expression of ET-1 and SCF in DPC, the higher ability of DPC to induce hair follicle regeneration. CONCLUSION: The expression strength of ET-1 and SCF is related to the ability of DPC inducing hair follicle regeneration. FAU - Lu, Zhong-fa AU - Lu ZF AD - Department of Dermatology, the Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China. FAU - Wu, Jin-jin AU - Wu JJ FAU - Liu, Rong-qing AU - Liu RQ FAU - Zhong, Bai-yu AU - Zhong BY FAU - Zheng, Min AU - Zheng M LA - chi PT - English Abstract PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - China TA - Zhejiang Da Xue Xue Bao Yi Xue Ban JT - Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences JID - 100927946 RN - 0 (Endothelin-1) RN - 0 (Stem Cell Factor) RN - 103107-01-3 (Fibroblast Growth Factor 2) SB - IM MH - Endothelin-1/*analysis/genetics MH - Fibroblast Growth Factor 2/*analysis/genetics MH - Hair Follicle/*chemistry/cytology/physiology MH - Humans MH - Immunohistochemistry MH - In Situ Hybridization MH - Stem Cell Factor/*analysis/genetics EDAT- 2004/07/23 05:00 MHDA- 2004/10/22 09:00 CRDT- 2004/07/23 05:00 PHST- 2004/07/23 05:00 [pubmed] PHST- 2004/10/22 09:00 [medline] PHST- 2004/07/23 05:00 [entrez] AID - 10.3785/j.issn.1008-9292.2004.04.005 [doi] PST - ppublish SO - Zhejiang Da Xue Xue Bao Yi Xue Ban. 2004 Jul;33(4):296-9. doi: 10.3785/j.issn.1008-9292.2004.04.005.