PMID- 15295251
OWN - NLM
STAT- MEDLINE
DCOM- 20050217
LR  - 20190911
IS  - 1535-1815 (Electronic)
IS  - 0749-5161 (Linking)
VI  - 20
IP  - 8
DP  - 2004 Aug
TI  - Accidental ecstasy poisoning in a toddler.
PG  - 534-5
AB  - A child of 14 months accidentally swallowed a portion of an Ecstasy pill. Forty 
      minutes after ingestion, he started a generalized convulsion. He also presented 
      hyperthermia (38 degrees C), hypertension, tachycardia (130 bpm), ventricular 
      extrasystoles, tachypnea (50 rpm), and mydriasis. At the hospital 5 hours later, 
      the urine levels of amphetamine/metamphetamine were >16 mg/L. He was treated with 
      general support measures and benzodiazepines intravenously and admitted to the 
      pediatric intensive care unit. During the first 12 hours, he continued with 
      hypertension, tachycardia, and long periods of trigeminy, without hemodynamic 
      repercussion. He was discharged fully recovered. Gas chromatography/mass 
      spectrometry analysis (8 hours after ingestion) showed a serum level of 3,4 
      methylenedioximethylamphetamine (MDMA) of 0.591 mg/L. The 3 cases described in 
      the literature have shown a good evolution of Ecstasy poisoning in toddlers and 
      infants, despite an initial critical situation. Regarding adults, the toddler 
      intoxication seems to present symptoms sooner (20 to 30 minutes), having as an 
      initial manifestation convulsions. However, great care must be taken on 
      accidental ingestion of these attractive design pills.
FAU - Melian, Abian Montesdeoca
AU  - Melian AM
AD  - Pediatric Intensive Care Unit, Hospital Universitario de Canarias, Tenerife, 
      Spain.
FAU - Burillo-Putze, Guillermo
AU  - Burillo-Putze G
FAU - Campo, Candelaria Gonzalez
AU  - Campo CG
FAU - Padron, Agustin Gonzalez
AU  - Padron AG
FAU - Ramos, Carlos Ormazabal
AU  - Ramos CO
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Pediatr Emerg Care
JT  - Pediatric emergency care
JID - 8507560
RN  - 12794-10-4 (Benzodiazepines)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Accidents, Home
MH  - Benzodiazepines/therapeutic use
MH  - Cardiac Complexes, Premature/chemically induced
MH  - Combined Modality Therapy
MH  - Fever/chemically induced
MH  - Humans
MH  - Hypertension/*chemically induced
MH  - Infant
MH  - Male
MH  - Mydriasis/chemically induced
MH  - N-Methyl-3,4-methylenedioxyamphetamine/blood/*poisoning
MH  - Oxygen Inhalation Therapy
MH  - Poisoning/blood/drug therapy/therapy
MH  - Respiration Disorders/chemically induced
MH  - Seizures/*chemically induced
MH  - Tachycardia/*chemically induced
EDAT- 2004/08/06 05:00
MHDA- 2005/02/18 09:00
CRDT- 2004/08/06 05:00
PHST- 2004/08/06 05:00 [pubmed]
PHST- 2005/02/18 09:00 [medline]
PHST- 2004/08/06 05:00 [entrez]
AID - 00006565-200408000-00009 [pii]
AID - 10.1097/01.pec.0000136072.37575.19 [doi]
PST - ppublish
SO  - Pediatr Emerg Care. 2004 Aug;20(8):534-5. doi: 
      10.1097/01.pec.0000136072.37575.19.