PMID- 15299201
OWN - NLM
STAT- MEDLINE
DCOM- 20050217
LR  - 20191108
IS  - 1046-3976 (Print)
IS  - 1046-3976 (Linking)
VI  - 15
IP  - 2
DP  - 2004 Summer
TI  - Combined sellar fibrosarcoma and prolactinoma with neuronal metaplasia: report of 
      a case unassociated with radiotherapy.
PG  - 149-58
AB  - We report the occurrence of a primary pituitary fibrosarcoma causally unrelated 
      to radiotherapy, admixed in association with a prolactin cell pituitary adenoma 
      showing neuronal metaplasia. These unique findings were associated with multiple 
      endocrine neoplasia type 1 (MEN 1). Primary fibrosarcoma involving the sella is a 
      very rare tumor. The majority of cases have been associated with prior 
      irradiation of either a pituitary adenoma or a craniopharyngioma. Pituitary 
      adenoma with neuronal metaplasia is also rare and usually occurs in the setting 
      of acromegaly. Despite the intimate association of both elements in our lesion, 
      no transition of adenoma to sarcoma was demonstrable by immunohistochemistry or 
      in situ hybridization studies.
FAU - Moro, Mario
AU  - Moro M
AD  - Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA.
FAU - Giannini, Caterina
AU  - Giannini C
FAU - Scheithauer, Bernd W
AU  - Scheithauer BW
FAU - Lloyd, Ricardo V
AU  - Lloyd RV
FAU - Restall, Paul
AU  - Restall P
FAU - Eagleton, Carl
AU  - Eagleton C
FAU - Law, Andrew J
AU  - Law AJ
FAU - Kovacs, Kalman
AU  - Kovacs K
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Endocr Pathol
JT  - Endocrine pathology
JID - 9009288
SB  - IM
MH  - Adult
MH  - Fatal Outcome
MH  - Fibrosarcoma/*complications/pathology/surgery
MH  - Humans
MH  - Immunohistochemistry
MH  - In Situ Hybridization
MH  - Male
MH  - Metaplasia
MH  - Multiple Endocrine Neoplasia Type 1/*complications/pathology
MH  - Nerve Tissue/*pathology
MH  - Pituitary Neoplasms/*complications/pathology/surgery
MH  - Prolactinoma/*complications/pathology/surgery
RF  - 68
EDAT- 2004/08/10 05:00
MHDA- 2005/02/18 09:00
CRDT- 2004/08/10 05:00
PHST- 2004/08/10 05:00 [pubmed]
PHST- 2005/02/18 09:00 [medline]
PHST- 2004/08/10 05:00 [entrez]
AID - EP:15:2:149 [pii]
AID - 10.1385/ep:15:2:149 [doi]
PST - ppublish
SO  - Endocr Pathol. 2004 Summer;15(2):149-58. doi: 10.1385/ep:15:2:149.