PMID- 15303438
OWN - NLM
STAT- MEDLINE
DCOM- 20040903
LR  - 20110726
IS  - 0301-4894 (Print)
IS  - 0301-4894 (Linking)
VI  - 105
IP  - 7
DP  - 2004 Jul
TI  - [Guide line for the treatment of stage I and stage II non small cell lung 
      cancer].
PG  - 392-403
AB  - Evidence based treatment modalities should be established as more than 55,000 
      patients die of lung cancer every year and its number is increasing. For stage I 
      and stage II non small cell lung cancer (NSCLC), surgery is strongly recommended 
      if there are no contraindications such as impaired pulmonary function and other 
      medical disorders. Although lobectomy (bilobectomy or pneumonectomy) with 
      mediastinal lymphnode dissection is standard operation for stage I and stage II 
      NSCLC, limited operation (segmentectomy or extended segmentectomy) for 
      peripherally located small sized cancer (less than 2 to 3) is now being performed 
      to assess if there is survival difference between standard operation. Also 
      numbers of patients undergoing video-assisted thoracoscopic surgery (VATS) is 
      increasing and studies to compare postoperative survival rate and postoperative 
      quality of life with standard operation is performed. To improve postoperative 
      survival, pre and postoperative treatment such as chemotherapy, radiotherapy or 
      combination of these treatments have been undertaken. Very recently usefulness of 
      postoperative adjuvant chemotherapy with Uracil-Tegafur for stage I adenocecinoma 
      was reported from Japan. For patients with stage I and stage II NSCLS in whom 
      operation is not feasible for medical reasons, radical radiation therapy is 
      recommended.
FAU - Kobayashi, Koichi
AU  - Kobayashi K
AD  - Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Nihon Geka Gakkai Zasshi
JT  - Nihon Geka Gakkai zasshi
JID - 0405405
SB  - IM
MH  - Carcinoma, Non-Small-Cell Lung/pathology/radiotherapy/surgery/*therapy
MH  - Combined Modality Therapy
MH  - Evidence-Based Medicine/classification
MH  - *Guideline Adherence
MH  - Humans
MH  - Lung Neoplasms/pathology/radiotherapy/surgery/*therapy
MH  - Lymph Node Excision
MH  - *Neoplasm Staging
MH  - Pneumonectomy
MH  - Pulmonary Surgical Procedures/methods
MH  - Survival Rate
EDAT- 2004/08/12 05:00
MHDA- 2004/09/04 05:00
CRDT- 2004/08/12 05:00
PHST- 2004/08/12 05:00 [pubmed]
PHST- 2004/09/04 05:00 [medline]
PHST- 2004/08/12 05:00 [entrez]
PST - ppublish
SO  - Nihon Geka Gakkai Zasshi. 2004 Jul;105(7):392-403.