PMID- 1530347
OWN - NLM
STAT- MEDLINE
DCOM- 19921020
LR  - 20131121
IS  - 0385-0684 (Print)
IS  - 0385-0684 (Linking)
VI  - 19
IP  - 10 Suppl
DP  - 1992 Aug
TI  - [Intra-arterial chemotherapy of local recurrence and non-curative case of 
      colorectal cancer].
PG  - 1745-8
AB  - Twelve colorectal cancer patients, including 9 with local recurrent cancer and 3 
      with remnant cancer after surgery, were treated with intraarterial chemotherapy. 
      Three cases were treated with MMC injection alone, 1 case with MMC combined with 
      irradiation (MMC-R) and 8 cases with ADM combined with irradiation (ADM-R). In 7 
      evaluable patients, the response rate was 28.6% with 1 CR case, 1 PR case and 5 
      NC cases. The 2 cases treated with ADM-R were successful. Six of 8 patients 
      treated with ADM-R survived more than 1 year, while all 4 patients treated with 
      MMC or MMC-R died within 8 months. The cumulative survival rate after ADM-R 
      treatment was 44% at 24 months. It is suggested that the combination of 
      intra-arterial chemotherapy and radiation therapy is an effective treatment for 
      local recurrence and non-curative cases of colorectal cancer.
FAU - Hashimoto, M
AU  - Hashimoto M
AD  - Dept. of Surgery, Social Insurance Saitama Chuo Hospital.
FAU - Murayama, Y
AU  - Murayama Y
FAU - Sano, M
AU  - Sano M
FAU - Katai, H
AU  - Katai H
FAU - Maeda, K
AU  - Maeda K
FAU - Sakai, S
AU  - Sakai S
FAU - Koh, J
AU  - Koh J
FAU - Yamamoto, O
AU  - Yamamoto O
FAU - Hosoda, Y
AU  - Hosoda Y
FAU - Suzuki, K
AU  - Suzuki K
AU  - et al.
LA  - jpn
PT  - English Abstract
PT  - Journal Article
PL  - Japan
TA  - Gan To Kagaku Ryoho
JT  - Gan to kagaku ryoho. Cancer & chemotherapy
JID - 7810034
RN  - 50SG953SK6 (Mitomycin)
RN  - 80168379AG (Doxorubicin)
SB  - IM
MH  - Chemotherapy, Adjuvant
MH  - Colonic Neoplasms/*drug therapy/mortality/radiotherapy
MH  - Doxorubicin/*administration & dosage
MH  - Humans
MH  - Infusions, Intra-Arterial
MH  - Mitomycin/*administration & dosage
MH  - Neoplasm Recurrence, Local/*drug therapy
MH  - Prognosis
MH  - Radiotherapy Dosage
MH  - Rectal Neoplasms/*drug therapy/mortality/radiotherapy
MH  - Survival Rate
EDAT- 1992/08/01 00:00
MHDA- 1992/08/01 00:01
CRDT- 1992/08/01 00:00
PHST- 1992/08/01 00:00 [pubmed]
PHST- 1992/08/01 00:01 [medline]
PHST- 1992/08/01 00:00 [entrez]
PST - ppublish
SO  - Gan To Kagaku Ryoho. 1992 Aug;19(10 Suppl):1745-8.