PMID- 15305871
OWN - NLM
STAT- MEDLINE
DCOM- 20041014
LR  - 20181113
IS  - 0953-816X (Print)
IS  - 1460-9568 (Electronic)
IS  - 0953-816X (Linking)
VI  - 20
IP  - 4
DP  - 2004 Aug
TI  - Differential activation of glomeruli in the ferret's main olfactory bulb by anal 
      scent gland odours from males and females: an early step in mate identification.
PG  - 1025-32
AB  - Peripheral anosmia was previously found to disrupt sex discrimination and partner 
      preference in male and female ferrets. Here we show directly that volatile anal 
      scent gland odourants from male and female ferrets activated overlapping but 
      distinguishable clusters of glomeruli located in the ventral-caudal portion of 
      the main olfactory bulb (MOB) of breeding ferrets of both sexes. No glomerular 
      activation was seen in the accessory olfactory bulb (AOB). The profile of MOB 
      glomerular activation induced in oestrous females by male anal scents was very 
      similar to that induced by direct contact with a male during mating, and 
      oestrogen treatment failed to alter the profile of glomerular activation induced 
      in ovo-hysterectomized females by male anal scents. In rodents, 'atypical' MOB 
      glomeruli, which have dense acetylcholinesterase (AChE) activity in the neuropil, 
      may be activated by body odours from conspecifics. No such AChE-staining 
      'atypical' glomeruli were found in the ferret's MOB, suggesting that in this 
      carnivore they do not constitute a subset of MOB glomeruli that respond to body 
      odourants. In ferrets of both sexes, volatile body odourants that are detected by 
      the main as opposed to the vomeronasal-AOB accessory olfactory system may play a 
      critical role in mate identification.
FAU - Woodley, Sarah K
AU  - Woodley SK
AD  - Department of Biology, Boston University, 5 Cummington St., Boston, MA 02215, 
      USA.
FAU - Baum, Michael J
AU  - Baum MJ
LA  - eng
GR  - R01 HD021094/HD/NICHD NIH HHS/United States
GR  - R01 HD021094-17/HD/NICHD NIH HHS/United States
GR  - DC00426/DC/NIDCD NIH HHS/United States
GR  - HD21094/HD/NICHD NIH HHS/United States
GR  - F32 DC000426/DC/NIDCD NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - France
TA  - Eur J Neurosci
JT  - The European journal of neuroscience
JID - 8918110
RN  - 0 (Pheromones)
SB  - IM
MH  - Anal Sacs/*metabolism/physiology
MH  - Animals
MH  - Female
MH  - Ferrets/*metabolism/physiology
MH  - Male
MH  - Olfactory Bulb/*metabolism/physiology
MH  - Pheromones/*metabolism/physiology
MH  - Sexual Behavior, Animal/*physiology
PMC - PMC1237011
MID - NIHMS2994
EDAT- 2004/08/13 05:00
MHDA- 2004/10/16 09:00
PMCR- 2008/01/04
CRDT- 2004/08/13 05:00
PHST- 2004/08/13 05:00 [pubmed]
PHST- 2004/10/16 09:00 [medline]
PHST- 2004/08/13 05:00 [entrez]
PHST- 2008/01/04 00:00 [pmc-release]
AID - EJN3571 [pii]
AID - 10.1111/j.1460-9568.2004.03571.x [doi]
PST - ppublish
SO  - Eur J Neurosci. 2004 Aug;20(4):1025-32. doi: 10.1111/j.1460-9568.2004.03571.x.